Chancellors Challenge Winners 2018
Faculty has been awarded EMBO Fellowship
Faculty have received an International Grant under GCC
Best Placement Brochure Award
Best Institute in Pharmacy Award by DNA Innovative Education Leadership Awards
Medicinal, Computational chemistry, Drug Metabolism and Toxicity
022-42332000 (Extn- 2018)
Total in years 6
(Industry – 2.5 years, Academics- 3.5 years)
During my M.S. and Ph. D. at NIPER, SAS Nagar, I have developed expertise in drug design, organic synthesis, and applications of quantum chemistry in chemical reaction/ kinetics, drug metabolism prediction and properties of novel boron containing compounds. These skills were later applied in explaining the control of redox-potentials, drug metabolism and drug-drug interactions during my first Postdoc at IISc, Bangalore (unpublished data). At AstraZeneca, UK I have investigated properties of novel five membered azaborole heterocycles both theoretically and experimentally. I have also reviewed recent methods of predicting drug metabolism catalyzed by CYP450 and non-CYP450 enzymatic systems. Toxicity of selected phenolic natural products have been investigated using WebMO/ GAMESS programs. Currently I am involved in developing drug toxicity and metabolism prediction models using novel toxicity indices and machine learning methods.
1. “Studies on the Hepatotoxicity of Phenolic Natural Products” 1st Indian conference of the International Society for Study of Xenobiotics (ISSX). 1-3 September 2016 at JN Tata Auditorium, Indian Institute of Science, Bangalore.
2. “Toxic Metabolite Formation from Troglitazone (TGZ): New Insights from a DFT Study and Design of Potentially Non-Toxic Analogues” An international conference on “Applied Theory on Molecular Systems (ATOMS) 2011” 2-5th November 2011 at IICT, Hyderabad, India.
3. “Design and Synthesis of Y-Shaped PPAR-γ activators”, at Chemical Research Society of India, North Zone meeting, September 22nd to 24th, 2011 Jammu, India.
He has guided 2 M.Pharm. students for their research projects.
Member of Royal Society of Chemistry (MRSC)