Dr. Sinjini Sarkar

Qualification              : M. Pharm., Ph.D.

Specialization             : Pharmacology

E mail                           : sinjini.sarkar@nmims.edu

Phone                          : 022-42332000 (Extn-  2093)

Experience                  : 7.5 (Research – 6+ years, Academics-2.5 years)

Dr. Sinjini Sarkar is currently serving as an Assistant Professor of Pharmacology, at SPP School of Pharmacy and Technology Management, SVKM's NMIMS Deemed to be University, Mumbai. She has completed her Ph.D. from Jadavpur University, Kolkata in May, 2023. During her Ph.D she had received a Young Scientist Fellowship from Department of Health Research, GoI. Her research focused on identifying novel genetic mutations and protein expressions in ovarian carcinoma, shedding light on potential biomarkers for clinical efficacy and related toxicity. Additionally, she conducted comprehensive assessments of chemotherapy outcomes and quality of life among Indian women with ovarian carcinoma. Currently, she is working on preclinical models of cancer and anti-cancer drug development. She has published in international peer-reviewed journals, like Chromosome Research, Supportive Care in Cancer, International Journal of Biological Macromolecules, Naunyn Schmiedberg journal of Pharmacology, Supportive Care in Cancer and Clinical and Translational Oncology etc. She has also presented her work at international conferences like FIGO World Congress and ESMO Asia Congress, from which her abstracts were published in International Journal of Gynecology & Obstetrics (IJGO) and Annals of Oncology. She serves as a reviewer for IJBIOMAC, Medical Oncology, Heliyon, Discover Oncology, Frontiers in Pharmacology, and Discover Oncology to name a few. She has also co-supervised several M. Pharm, M.Sc and B. Tech (Biotech) students for their dissertations and higher study applications. Her academic and research experiences have been complemented by her involvement in placement, counselling, organizing & volunteering blood donation camps and participation in sports and cultural activities.

Interest areas:

• Molecular Pharmacology
• Biomarker Discovery
• Clinical Research

Research

• Publications – 13 (International-12 , National- 01)
• Book Chapters- 01
• Presentations- Total number (International- 02, National- 03)
• University Seed Funding Scheme– 01
  • Ongoing (Granted Rs. 2,84,338/-)
• Government funded projects – 01
  • Completed (Granted amount in Rs. 32,00,000/- by Department of Health Research, MoHFW, GoI. Study site: Chittaranjan National Cancer Institute, Kolkata)

Conferences/Workshops/Seminars attended : 13

• Poster presentation: Simran Soni, Sinjini Sarkar, Ginpreet Kaur. Potentials of Clemastine in the Treatment of Neuro-inflammation Using NLRP3 Pathway. Presented by Ms. Simran Soni (PhD Scholar under supervision of Prof. Ginpreet Kaur in NMIMS, Mumbai), at 15th Annual Conference of the South Asian College of Clinical Pharmacology SAC-ACCP- 2025 Goa, India held on 3rd-5th Jan, 2025.
• Poster presentation: 2nd Prize recipient, Sinjini Sarkar, Santosh K Behera, Vilas D. Nasare. Exploring the potential of MAD2L1 in ovarian cancer outcomes: clinical estimations and computational analysis. Presented at Workshop on Computational Oncology: Integrating experiments and computational models (Wocon- 2024) [17th -18th Dec, 2024], organized by the Indian Institute of Technology (Banaras Hindu University) Varanasi, in collaboration with The Param Hansa Centre for Computational Oncology (PHCCO), Indian Institute of Science (IISc), Bengaluru.
• Poster presentation: S. Sarkar, P.K. Sahoo, T. Mistry, R. Pal, S. Ghosh, T. Choudhury, S. Mahata, M. Vernekar, T. Bera, K.K. Mukherjee, P. Nath, V.D. Nasare, BUB1 (2530C>T) polymorphism and expression affects chemotherapy response and predicts poor prognosis in advanced epithelial ovarian cancer, presented at ESMO Asia Congress held on 2-4th December, 2022. Abstract published: Annals of Oncology 2022; 33(Suppl. 9): S1508-S1509. DOI: https://doi.org/10.1016/j.annonc.2022.10.223 (IF: 51.769)
• Oral presentation: Sinjini Sarkar, Pranab Kumar Sahoo, Sushmita Ghosh, Sutapa Mahata, Ranita Pal, Tanuma Mistry, Trisha Choudhury, Manisha Vernekar, Puja Chatterjee, Partha Nath, Kalyan K Mukherjee, Vilas D Nasare. Clinical outcomes of paclitaxel-carboplatin chemotherapy with impact of mitotic checkpoint proteins in advanced ovarian cancer patients, presented at 5th International Conference on Nutraceuticals for Cancer and Other Chronic Disease (2022) Organized by Department of Zoology, University of Delhi, October 7-9,2022, IL-8 Page 48.
• Poster presentation: Sahoo, P. K., Sarkar, S., Mahata, S., Pal, R., Mistry, T., Ghosh, S., Choudhury, T., Bhowmick, A. K., Mukherjee, K. K., Datta, S., & Nasare,V. D. (2022). Clinical Efficacy and Quality of Life of Oral Cancer Patients Treated with Paclitaxel/Cisplatin/5-FU Vs Paclitaxel/Carboplatin Chemotherapeutic Regimens in a Tertiary Cancer Center in Eastern India, Journal of the National Comprehensive Cancer Network, 20(3.5), CLO22-081-CLO22-081. Retrieved Apr 7, 2022 (IF: 12.693)
• Poster presentation: Sinjini Sarkar; Pranab Kumar Sahoo; Sutapa Mahata; Ranita Pal; Sushmita Ghosh; Tanmoy Bera; Vilas D. Nasare., MAD1L1 and MAD2L2 polymorphism in advanced ovarian carcinoma patients and its clinical impact, presented at FIGO XXIII World Congress of Gynaecology and Obstetrics held on 21-28th Oct, 2021. Abstract published: Int J Gynecol Obstet. 2021;155(Suppl. 2):127–532. DOI: 10.1002/ijgo.13886 (IF: 4.4)
• Poster presentation: Third prize winner, at National workshop on ‘Pharmacists for Healthy India’ organized by IPA, Bengal Branch and Jadavpur University on 27^th Nov, 2016. Topic of Poster: ‘Interference of autophagy in regulation of cytokine production: Influence on defense against microorganisms.’
• Completed a 5-Day Hands-on course on Nano-formulation and their characterizations at SPPSPTM, Mumbai from 1st -5th July, 2024.
• Attended the 2-days IIT Bombay BioPharma Summit, 2023 on 23^rd and 24^th Nov, 2023.
• Completed a 5-day Foundation Course in Clinical Research conducted by Tata Consultancy services at TCS, Thane as an Academia Industry Programme, in August, 2023.
• Participated in the Pre-conference Workshop on ‘Clinical Drug Research, Good Clinical Practice and Ethics’ at the 27^th Annual Conference, Indian Pharmacological Society, WB on 7^th Feb, 2018.
• Participated in the Pre-conference Workshop on ‘Adverse Drug Reaction Monitoring and Safe Therapy’ at Annual State Conference of Indian Pharmacological Society, WB on 17th Feb, 2016.
• Attended seminar on ‘Facets of Insilico Chemical Biology for Novel Therapeutics’ held at CSIR-IICB, Kolkata, on 18th June, 2013.

Academic activities

• Appointed as Resource person for 2 lectures at Pharmacology Summer School organized by SPP SPTM, Mumbai, from 1^st -5^th July, 2025.
• Appointed as Resource person for 1 session of National e-Faculty Development Program (e-FDP) on "Next-Gen Therapeutics: Emerging Trends in Drug Discovery and Biotechnology” held from June 9–13, 2025, by Amity Institute of Pharmacy, Amity University, Kolkata.
• Previously served as a member of Seed Funding Monitoring Committee and currently serving as a member of Institution Innovation Council, at SPP SPTM, Mumbai.
• Appointed as External referee conducting Viva-Voce examinations of B. Pharm (Pharmacology and Human Anatomy & Physiology) students from The Neotia University, West Bengal and NSHM College of Pharmaceutical Technology, Kolkata.
• Guest lecturer appointed by Pfizer for Pharmacy engagement programme in Mumbai location for pharmacists working at Breach Candy hospital, Mumbai in October 2023.

Awards

• Awarded Young Scientist Fellowship (2018) from Department of Health Research, MoHFW, GoI
• Awarded College Topper, M. Pharm (2017), NSHM College of Pharmaceutical Technology, Kolkata
• Qualified Graduate Pharmacy Aptitude Test (2016)

Professional Memberships

• Registered Pharmacist, West Bengal State Pharmacy Council
• Member, European Society of Medical Oncology

Recent Publications

• Pal R, Sarkar S, Choudhury T, Ghosh M, Vernekar M, Nath P, Nasare VD. Implication of microRNA-regulated PTEN expression in the clinico-pathology & survival outcomes in advanced ovarian cancer. Indian Journal of Medical research, (2025); 161: 521-531. (IF: 2.5)
• Choudhury T, Pal R, Ghosh M, Chatterjee S, Sarkar S, Vernekar M, Nath P, Nasare VD. Clinicopathological insights and prognostic implications of DEK in association with apoptosis-regulating factors in ovarian cancer. Clin Transl Oncol. 2025 May 20. doi: 10.1007/s12094-025-03944-8. Epub ahead of print. PMID: 40392449. (IF: 2.8)
• Sarkar S. Pathological role of RAGE underlying progression of various diseases: its potential as biomarker and therapeutic target. Naunyn-Schmiedeberg's archives of pharmacology, (2024).10.1007/s00210-024-03595-6. Advance online publication. https://doi.org/10.1007/s00210-024-03595-6. (IF: 3.1) [Review]
• Sarkar S, Pal R, Choudhury T, Vernekar M, Nath P, Nasare VD. Genetic Variations Affect Chemotherapy Outcomes: A Role of the Spindle-assembly Checkpoint. Indian J Public Health. 2024 Apr 1;68(2):314-317. doi: 10.4103/ijph.ijph_809_23. Epub 2024 Jun 29. PMID: 38953826. (IF: 0.9)
• Sahoo PK, Bhowmick AK, Sarkar S, Mahata S, Pal R, Mistry T, Ghosh S, Choudhury T, Kumar RS, Mondal S, Datta S, Nath P, Mukherjee KK, Nasare VD. Outcomes of 3-year follow up with induction vs first line chemotherapy in oral cancer patients: An observational hospital-based study. J Cancer Res Ther. 2024 Jan 22. doi: 10.4103/jcrt.jcrt_2179_22. Epub ahead of print. PMID: 38261440. (IF: 1.4)
• Mistry T, Nath A, Pal R, Ghosh S, Mahata S, Kumar Sahoo P, Sarkar S, Choudhury T, Nath P, Alam N, Nasare VD. Emerging Futuristic Targeted Therapeutics: A Comprising Study Towards a New Era for the Management of TNBC. Am J Clin Oncol. 2024 Mar 1; 47(3):132-148. doi: 10.1097/COC.0000000000001071. Epub 2023 Dec 19. PMID: 38145412. (IF: 1.6) [Review]
• Mahata S, Sahoo PK, Pal R, Sarkar S, Mistry T, Ghosh S, Nasare VD. PIM1/STAT3 axis: a potential co-targeted therapeutic approach in triple-negative breast cancer. Med Oncol. 2022 May 15; 39(5):74. doi: 10.1007/s12032-022-01675-2. PMID: 35568774. (IF: 3.738) [Review]
• Sarkar S, Sahoo PK, Pal R, Mistry T, Mahata S, Chatterjee P, Vernekar M, Mandal S, Bera T, Nasare VD. Assessment of quality of life among advanced ovarian cancer patients in a tertiary care hospital in India. Support Care Cancer. 2022 Apr; 30(4):3371-3378. doi: 10.1007/s00520-021-06735-3. Epub 2022 Jan 6. PMID: 34988703. (IF-3.359)
• Mahata S, Behera SK, Kumar S, Sahoo PK, Sarkar S, Fazil MHUT, Nasare VD. In-silico and in-vitro investigation of STAT3-PIM1 heterodimeric complex: Its mechanism and inhibition by curcumin for cancer therapeutics. Int J Biol Macromol. 2022 May 31; 208:356-366. Doi: 10.1016/j.ijbiomac.2022.03.137. Epub 2022 Mar 26. PMID: 35346675. (IF: 8.5)
• Sarkar S, Sahoo PK, Mahata S, Pal R, Ghosh D, Mistry T, Ghosh S, Bera T, Nasare VD. Mitotic checkpoint defects: en route to cancer and drug resistance. Chromosome Res. 2021 Jun; 29(2):131-144. doi: 10.1007/s10577-020- 09646-x. Epub 2021 Jan 6. PMID: 33409811. (IF-2.8) [Review]
• Sahoo PK, Sarkar S, Ghosh D, Mahata S, Pal R, Mistry T, Ghosh S, Roy A, Bucha H, Mandal S, Nasare VD. Premalignant and malignant lesions of oral cavity in eastern India: a hospital-based study. Eur J Cancer Prev. 2020 Nov 27. (IF: 2.4)
• Ghosh, D., Mahata, S., Sahoo, P.K., Sarkar, S., Roy, A., Datta, K., Vernekar, M., Mandal, S., & Nasare, V.D. (2019). Socio-demographic Characteristics and Use of Pap Smear for Cervical Cancer Screening among Women of Eastern Part of India. Indian Journal of Gynecologic Oncology, 17. (IF:0.4)
• Sarkar S. (2019). Short-term treatment of elastase-LPS induced exacerbation model of emphysema in mice with docosahexaenoic acid, a precursor of anti-inflammatory autacoids. Int J Pharm Sci & Res; 10(4): 1775-83. (IF: 1.0).

Book Chapter

• Roy Pradhan, S., Mahata, S., Ghosh, D., Kumar Sahoo, P., Sarkar, S., Pal, R., & D. Nasare, V. (2020). Human Papillomavirus Infections in Pregnant Women and Its Impact on Pregnancy Outcomes: Possible Mechanism of Self-Clearance. IntechOpen. doi: 10.5772/intechopen.90197.