Dr. Sinjini Sarkar

Assistant Professor

Qualification : M. Pharm., Ph.D.

Specialization : Pharmacology

E mail : sinjini.sarkar@nmims.edu

Phone : 022-42332000 (Extn-2029)

Experience : 7.5 (Research – 6+ years, Academics-2.5 years)

Dr. Sinjini Sarkar holds a Ph.D. (Pharmacy) from Jadavpur University, Kolkata, and was awarded the Young Scientist Fellowship from the Department of Health Research, Government of India, while working at Chittaranjan National Cancer Institute, Kolkata. Her expertise spans pharmacology, cancer biology, and molecular biology techniques including nucleic acid and protein isolation, PCR (all types), RFLP, sanger sequencing, histopathology, immunohistochemistry, bioinformatics, and pharmacogenomics-based biomarker discovery. She has trained and supervised UG and PG students and served as faculty at reputed pharmacy institutions in Kolkata and Mumbai. Her recent work integrates experimental and computational approaches of gene expression profiling, and preclinical models to identify biomarkers and therapeutic targets in chemotherapy-associated complications and cancer progression.

Interest areas:

Molecular Pharmacology
Biomarker discovery in oncology
Clinical research

Research

Publications – 13 (International-12 , National- 01)
Book Chapters- 02
- Roy Pradhan, S., Mahata, S., Ghosh, D., Kumar Sahoo, P., Sarkar, S., Pal, R., & D. Nasare, V. (2020). Human Papillomavirus Infections in Pregnant Women and Its Impact on Pregnancy Outcomes: Possible Mechanism of Self-Clearance. IntechOpen. doi: 10.5772/intechopen.90197
- Sarkar, S., Mukherjee, S., Chatterjee, S., Basu, B., Karati, D., & Prajapati, B. (2025). Nanocarrier in Gene Therapy. In Nanocarriers for Nucleic Acids and Proteins (1st ed., pp. 24). CRC Press.
Presentations- Total number (International- 02, National- 02)
Government funded projects – 01 (From previous institute)
University funded projects– 01 (Completed)
- SVKM’s NMIMS sanctioned Rs. 2,84,338/- on 29^th July, 2024 under their Seed Funding Scheme for an intramural project, for the period of one year.
Patents- NA

Conferences/Workshops/Seminars attended- 10

Poster presentation: Simran Soni, Sinjini Sarkar, Ginpreet Kaur. Potentials of Clemastine in the Treatment of Neuro-inflammation Using NLRP3 Pathway. Presented by Ms. Simran Soni (PhD Scholar under supervision of Prof. Ginpreet Kaur in NMIMS, Mumbai), at 15th Annual Conference of the South Asian College of Clinical Pharmacology SAC-ACCP- 2025 Goa, India held on 3^rd-5^th Jan, 2025.
Poster presentation: Sinjini Sarkar, Santosh K Behera, Vilas D. Nasare. Exploring the potential of MAD2L1 in ovarian cancer outcomes: clinical estimations and computational analysis. Presented at Workshop on Computational Oncology: Integrating experiments and computational models (Wocon- 2024) [17^th -18^th Dec, 2024], organized by the Indian Institute of Technology (Banaras Hindu University) Varanasi, in collaboration with The Param Hansa Centre for Computational Oncology (PHCCO), Indian Institute of Science (IISc), Bengaluru. (2^nd Prize recipient)
Poster presentation: Sinjini Sarkar; Pranab Kumar Sahoo; Sutapa Mahata; Ranita Pal; Sushmita Ghosh; Tanmoy Bera; Vilas D. Nasare., MAD1L1 and MAD2L2 polymorphism in advanced ovarian carcinoma patients and its clinical impact, presented at FIGO XXIII World Congress of Gynaecology and Obstetrics held on 21-28th Oct, 2021. Abstract published: Int J Gynecol Obstet. 2021; 155(Suppl. 2):127–532. DOI: 10.1002/ijgo.13886 (IF: 4.4)
Poster presentation: Sarkar, P.K. Sahoo, T. Mistry, R. Pal, S. Ghosh, T. Choudhury, S. Mahata, M. Vernekar, T. Bera, K.K. Mukherjee, P. Nath, V.D. Nasare, BUB1 (2530C>T) polymorphism and expression affects chemotherapy response and predicts poor prognosis in advanced epithelial ovarian cancer, presented at ESMO Asia Congress held on 2-4th December, 2022. Abstract published: Annals of Oncology 2022; 33(Suppl. 9): S1508-S1509. DOI: https://doi.org/10.1016/j.annonc.2022.10.223 (IF: 51.769)
Oral presentation: Sinjini Sarkar, Pranab Kumar Sahoo, Sushmita Ghosh, Sutapa Mahata, Ranita Pal, Tanuma Mistry, Trisha Choudhury, Manisha Vernekar, Puja Chatterjee, Partha Nath, Kalyan K Mukherjee, Vilas D Nasare. Clinical outcomes of paclitaxel-carboplatin chemotherapy with impact of mitotic checkpoint proteins in advanced ovarian cancer patients, presented at 5th International Conference on Nutraceuticals for Cancer and Other Chronic Disease (2022) Organized by Department of Zoology, University of Delhi, October 7-9,2022, IL-8 Page 48.
Poster presentation: Sahoo, P. K., Sarkar, S., Mahata, S., Pal, R., Mistry, T., Ghosh, S., Choudhury, T., Bhowmick, A. K., Mukherjee, K. K., Datta, S., & Nasare,V. D. (2022). Clinical Efficacy and Quality of Life of Oral Cancer Patients Treated with Paclitaxel/Cisplatin/5-FU Vs Paclitaxel/Carboplatin Chemotherapeutic Regimens in a Tertiary Cancer Center in Eastern India, Journal of the National Comprehensive Cancer Network, 20(3.5), CLO22-081-CLO22-081. Retrieved Apr 7, 2022 (IF: 12.693)
Poster presentation: Third prize winner, at National workshop on ‘Pharmacists for Healthy India’ organized by IPA, Bengal Branch and Jadavpur University on 27^th Nov, 2016. Topic of Poster: ‘Interference of autophagy in regulation of cytokine production: Influence on defense against microorganisms.’
Attended the 2-days IIT Bombay BioPharma Summit, 2023 on 23^rd and 24^thNov, 2023.
Completed a 5-day Foundation Course in Clinical Research conducted by Tata Consultancy services at TCS, Thane for a Academia Industry Programme, in August, 2023.

Academic activities

Appointed as Resource person for 2 lectures at Pharmacology Summer School organized by SPP SPTM, Mumbai, from 1st -5th July, 2025.
Appointed as Resource person for 1 session of National e-Faculty Development Program (e-FDP) on "Next-Gen Therapeutics: Emerging Trends in Drug Discovery and Biotechnology” held from June 9th-13th, 2025, by Amity Institute of Pharmacy, Amity University, Kolkata
Appointed as External referee conducting Viva-Voce examinations of B. Pharm (Pharmacology and Human Anatomy & Physiology) students from The Neotia University and NSHM College of Pharmaceutical Technology.
Guest lecturer appointed by Pfizer for Pharmacy engagement programme in Mumbai location for pharmacists working at Breach Candy hospital, Mumbai in October 2023.

Awards

Awarded Young Scientist Fellowship (2018) from Department of Health Research, MoHFW, GoI

Professional Memberships

Registered Pharmacist, West Bengal State Pharmacy Council
Member, Cochrane
Member, European Society for Medical Oncology (ESMO), Switzerland

Recent Publications

Sharma, V., Sarkar, S., & Singh, K. (2026). Synergistic topical therapy for squamous cell carcinoma via mixed micelles co-delivering 5-fluorouracil and genistein. Journal of Pharmaceutical Innovation, 21, 359. https://doi.org/10.1007/s12247-026-10589-9 (Impact Factor: 2.7)
Sarkar, S., Pal, R., Choudhury, T., Vernekar, M., Chatterjee, P., Mukherjee, K. K., Nath, P., Behera, S. K., Kumar, S., & Nasare, V. D. (2025). Checkpoint genes in check: Impact of BUB1, BUB1B, and MAD2 alterations on the treatment outcomes of advanced ovarian cancer. Journal of Current Oncological Trends, 2(1), 72–81. https://doi.org/10.4103/JCOT.JCOT_2_25
Pal, R., Sarkar, S., Choudhury, T., Ghosh, M., Vernekar, M., Nath, P., & Nasare, V. D. (2025). Implication of microRNA-regulated PTEN expression in the clinicopathology and survival outcomes in advanced ovarian cancer. Indian Journal of Medical Research, 161, 521–531. https://doi.org/10.25259/IJMR_1045_2024. (Impact Factor: 2.5)
Sarkar, S., Sahoo, P. K., Mahata, S., Pal, R., Ghosh, D., Mistry, T., Ghosh, S., Bera, T., & Nasare, V. D. (2021). Mitotic checkpoint defects: en route to cancer and drug resistance. Chromosome research: an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 29(2), 131–144. https://doi.org/10.1007/s10577-020-09646-x. (Impact Factor : 2.8)
Sarkar, S. (2024). Pathological role of RAGE underlying progression of various diseases: Its potential as biomarker and therapeutic target. Naunyn-Schmiedeberg's Archives of Pharmacology. Advance online publication. https://doi.org/10.1007/s00210-024-03595-6 (Impact Factor: 3.1)
Sarkar, S., Pal, R., Choudhury, T., Vernekar, M., Nath, P., & Nasare, V. D. (2024). Genetic variations affect chemotherapy outcomes: A role of the spindle assembly checkpoint. Indian Journal of Public Health. (Impact Factor: 0.9)
Sahoo, P. K., Bhowmick, A. K., Sarkar, S., Mahata, S., Pal, R., Mistry, T., Ghosh, S., Choudhury, T., Kumar, R. S., Mondal, S., Datta, S., Nath, P., Mukherjee, K. K., & Nasare, V. D. (2024). Outcomes of 3-year follow-up with induction vs first-line chemotherapy in oral cancer patients: An observational hospital-based study. Journal of Cancer Research and Therapeutics. Advance online publication. https://doi.org/10.4103/jcrt.jcrt_2179_22 (Impact Factor: 1.4)
Sarkar, S., Sahoo, P. K., Pal, R., Mistry, T., Mahata, S., Chatterjee, P., Vernekar, M., Mandal, S., Bera, T., & Nasare, V. D. (2022). Assessment of quality of life among advanced ovarian cancer patients in a tertiary care hospital in India. Supportive Care in Cancer, 30(4), 3371–3378. https://doi.org/10.1007/s00520-021-06735-3 (Impact Factor: 3.359)
Mahata, S., Behera, S. K., Kumar, S., Sahoo, P. K., Sarkar, S., Fazil, M. H. U. T., & Nasare, V. D. (2022). In silico and in vitro investigation of STAT3–PIM1 heterodimeric complex: Its mechanism and inhibition by curcumin for cancer therapeutics. International Journal of Biological Macromolecules, 208, 356–366. https://doi.org/10.1016/j.ijbiomac.2022.03.137 (Impact Factor: 8.025).
Sahoo, P. K., Sarkar, S., Ghosh, D., Mahata, S., Pal, R., Mistry, T., Ghosh, S., Roy, A., Bucha, H., Mandal, S., & Nasare, V. D. (2021). Premalignant and malignant lesions of oral cavity in eastern India: a hospital-based study. European journal of cancer prevention: the official journal of the European Cancer Prevention Organisation (ECP), 30(5), 393–399. https://doi.org/10.1097/CEJ.0000000000000640. (Impact Factor : 2.4)

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Dr. Sinjini Sarkar