Alka Raj Pandey

Qualification              : Ph.D.

Specialization            : Medicinal and Process Chemistry

E mail                         : alka.rajpandey@nmims.edu

Phone                         : 022-42332000 (Extn- 2093)

Experience                 : 1 year (Academics)

My doctorate research work was dedicated to "Isolation, characterization and synthesis of analogues of bioactive compounds from Indian Medicinal Plants”

Interest areas:

• Development of novel medicinally important NCEs.
• In silicobased drug designing
• Medicinal Chemistry: SAR development; Hit to lead library generation
• Isolation and characterisation of novel natural bioactive compounds.

Research

• Publications – Total number (International- 13)
• Presentations- Total number (International- 2, National-2)
• Government funded projects –1
  • Completed ("Isolation, characterization and synthesis of analogues of bioactive compounds from Indian Medicinal Plants”, funding agency-DST, amount in Rs.35 lacs)

Conferences/Workshops/Seminars attended- Total number.-04

Awards

• Gold medalist, M.S Pharm. (2015-2017), National Institute of Pharmaceutical Education and Researchh, Raebareli.
• Graduate Pharmacy Aptitude Test (GPAT) 2015, NIPER JEE 2015– All India Rank (AIR) 394
• Awarded with DST-INSPIRE Junior Research Fellowship and Senior Research Fellowship
• Incentive award by CSIR-CDRI Lucknow for best publication in ACS Journal of Medicinal Chemistry.

Professional Memberships

            Registered Pharmacist (Uttar Pradesh State Council)

            Member, American Chemical Society (ACS) (Category-Community Associate)  

Recent Publications

1. Alka Raj Pandey, Divya Rai, Suriya Pratap Singh, Ashish Kumar Tripathi, Anirban Sardar, Alisha Ansari, Anjali Mishra, Sudha Bhagwati, Rabi Sankar Bhatta, Mohammad Imran Siddiqi, Naibedya Chattopadhyay, Ritu Trivedi, and Koneni V. Sashidhara. Synthesis and Evaluation of Galloyl Conjugates of Flavanones as BMP-2 Upregulators with Promising Bone Anabolic and Fracture Healing Properties. J. Med. Chem.2021, 64, 12487-12505.

2. Alka Raj Pandey, Shadab Ahmad, Suriya Pratap Singh, Anjali Mishra, Amol Chhatrapati Bisen, Gaurav Sharma, Ishbal Ahmad, Sanjeev K. Shukla, Rabi Shankar Bhatta, Sanjeev Kanojiya, Akhilesh Kumar Tamrakar, Koneni V. Sashidhara. Furostanol saponins from Asparagus racemosus as potential hypoglycemic agents. Phytochemistry.2022, 201, 113286.

3. Alka Raj Pandey, Suriya Pratap Singh, Prince Joshi, Kunwar Satyadeep Srivastav, Smriti Srivastava, Kanchan Yadav, Ramesh Chandra, Amol Chhatrapati Bisen, Sristi Agrawal, Sachin Nashik Sanap, Rabi Sankar Bhatta, Renu Tripathi, Manoj Kumar Barthwal, Koneni V. Sashidhara. Design, synthesis and evaluation of novel pyrrole-hydroxybutenolide hybrids as promising antiplasmodial and anti-inflammatory agents. Eur. J. Med. Chem. 2023,254, 15340.

4. Alka Raj Pandey, Suriya Pratap Singh, Karthik Ramalingam, Kanchan Yadav, Amol Chhatrapati Bisen, Anjali Mishra, Rabi Sankar Bhatta, Mrigank Srivastava, Renu Tripathi, Neena Goyal, Koneni V. Sashidhara. Antileishmanial evaluation of triazole-butenolide conjugates: Design, synthesis, in vitro screening, SAR and in silico ADME predictions. RSC Med. Chem. 2023.

5. Shadab Ahmad, Alka Raj Pandey, Suriya Pratap Singh, Sushmita Singh, Koneni V. Sashidhara & Akhilesh K. Tamrakar. Antiglycation activity of β-glucogallin from Asparagus racemosus. Nat. Prod. Res. 2022, 36, 6329-6335.

6. Amit K. Rai, Suriya P. Singh, Alka Raj Pandey, Alisha Ansari, Shadab Ahmad, Koneni V. Sashidhara & Akhilesh K.Tamrakar. Flavonoids from Polyalthia longifoliaprevents advanced glycation end products formation and protein oxidation aligned with fructose-induced protein glycation. Nat. Prod. Res.2021, 35, 2921-2925.

7. Richa Sharma, Tulika Srivastava, Alka Raj Pandey, Tripti Mishra, Bhagyashri Gupta, Sabbu Sathish Reddy, Suriya P. Singh, T. Narender, Aradhya Tripathi, Balasubramanian Chandramouli, Koneni V. Sashidhara, Smriti Priya and Niti Kumar.Identification of Natural Products as Potential Pharmacological Chaperones for Protein Misfolding Diseases. ChemMedChem.2021, 16, 2146-2156.

8. Divya Rai, Ashish Kumar Tripathi, Anirban Sardar, Alka Raj Pandey, Shradha Sinha, Kunal Chutani, Geeta Dhaniya, Priyanka Kothari, Koneni V. Sashidhara, Ritu Triwedi.A novel BMP2 secretagogue ameliorates glucocorticoid induced oxidative stress in osteoblasts by activating NRF2 dependent survival while promoting Wnt/β-catenin mediated osteogenesis. Free. Radic. Biol. Med. 2022, 190, 124-147. 

9. Shadab Ahmad, Alka Raj Pandey, Amit K. Rai, Suriya Pratap Singh, Pawan Kumar, Sushmita Singh, Farah Gulzar, Ishbal Ahmad, Koneni V. Sashidhara, Akhilesh Kumar Tamrakar.Moringa oleifera impedes protein glycation and exerts reno-protective effects in streptozotocin-induced diabetic rats. J. Ethnopharmacol. 2023, 305, 116117.

10. Chirag Kulkarni, Shivani Sharma, Konica Porwal, Swati Rajput, SreyankoSadhukhan, Vaishnavi Singh, Akanksha Singh, Sanjana Baranwal, Saroj Kumar, Aboli Girme, Alka Raj Pandey, Suriya Pratap Singh, Koneni V. Sashidhara, Navin Kumar, Lal Hingorani and Naibedya Chattopadhyay. A standardized extract of Coleus forskohliiroot protects rats from ovariectomy-induced loss of bone mass and strength, and impaired bone material by osteogenic and anti-resorptive mechanisms. Front. Endocrinol (Lausanne).2023, 28, 14, 1130003.