Dr. Gargi Nikhil Vaidya

Qualification              : M.S (Pharm.), Ph.D.

Specialization             : Medicinal Chemistry

E-mail                         : gargi.vaidya@nmims.edu

Phone                         : 022-42332000 (Extn-2093) 

Her doctorate research work was dedicated to development of novel and sustainable methodologies for synthesis and functionalization of bioactive N-heterocycles in relevance to medicinal chemistry by the underlying principles of "Green chemical processes and micellar catalysis”.

Interest areas:

• Development of novel NCEs (Anti-cancer and Anti-diabetic)
• In silico based drug designing
• Medicinal Chemistry: SAR development; Hit to lead library generation
• Green Chemistry
• Heterocyclic Synthesis and Functionalization

Research

• Publications – Total number (International- 10, National-0)
• Patents- 1(Granted) and 1(Filled)
• Presentations- Total number (National- 1) 

Conferences/Workshops/Seminars attended- 3 

 Awards

• 2nd Price for Vikram Sarabhai Best Ph.D. Thesis Award 2023 with cash prize of 20,000/-Rs.; Organized by Vigynan Gurjari -Gujarat, India
• NIPER JEE 2017 – All India Rank (AIR) 3 (Chemical Science category) for PhD programme
• NIPER JEE 2015 – All India Rank (AIR) 65 for M.S.(Pharm.) programme
• Graduate Pharmacy Aptitude Test (GPAT) 2015 – All India Rank (AIR) 585
• IMDA AWARD for highest CGPA with cash prize of 5000 /- Rs for west zone (India)
• Gold medalist (University Topper), B. Pharm. (2011-2015), Institute of Pharmacy, Nirma University, Ahmedabad, Gujarat 

Professional Memberships

Registered Pharmacist (Gujarat State Council)

Member, American Chemical Society (ACS) (31823044; Category-Community Associate) 

Recent Publications

1. Dinesh Parshuram Satpute; Urjita Shirwadkar; Anil Kumar Tharalla; Sangita Dattatray Shinde; Gargi Nikhil Vaidya; Swarali Joshi; Priyanka Patel Vatsa; Alok Jain; Abhishek Singh; Rachana Garg; Amit Mandoli, Dinesh Kumar.* Discovery of Fluorinated 2-Styryl 4(3H)-quinazolinone as Potential Therapeutic Hit for Oral Cancer. Bioorg. Med. Chem. 2023, 81, 1177193. (I.F. 3.46)
2. Gargi Nikhil Vaidya, Shyam Kumar Lokhande, Sangita Dattatray Shinde, Dinesh Parshuram Satpute, Garvita Narang and Dinesh Kumar.* Aqueous Micelles Enabled, Nickel-Catalyzed Chemoselective C3-Allylation of (NH)-Indoles Employing Alcohols. Green Chem. 2022, 24, 4921- 4927. (I.F. 11.03).
3. Gargi Nikhil Vaidya, Ramesh Choudhary, Mithilesh Nagpure, Shyam Kumar Lokhande, Pooja Rana, Dinesh Kumar.* ‘In-water’, Nickel-Catalyzed Mild Preparation of Allylic Amines Employing Alcohols: Application to ‘All-water’ Synthesis of Pharmaceuticals. Green Chem. 2022, 24, 3977-3984. (I.F. 11.03). Highlighted in "2022 Green Chemistry Hot Articles.”
4. Dinesh Parshuram Satpute, Gargi Nikhil Vaidya, Shyam Kumar Lokhande, Sangita Dattatray Shinde, Shivkanya Madhavrao Bhujbal, Deep Rohan Chatterjee, Pooja Rana, Ashwini Venkatesh, Mithilesh Nagpure and Dinesh Kumar.* Organic Reactions in Aqueous Media Catalyzed by Nickel. Green Chem. 2021, 23, 6273-6300. (I.F. 11.03)
5. Gargi Nikhil Vaidya, Mithilesh Nagpure, Dinesh Kumar.* Borrowing Carbonate-Enabled Allylic Amination Reactions under Additive- and Reductant-Free Nickel Catalysis Employing Allylic Alcohols. ACS Sustain. Chem. Eng. 2021, 9, 1846–1855. (IF = 9.22).
6. Gargi Nikhil Vaidya, Pooja Rana, Ashwini V., Deep Rohan Chatterjee, Darshan R. Contractor, Dinesh Parshuram Satpute, Mithilesh Nagpure, Alok Jain*, Dinesh Kumar.* Paradigm Shift in Post-Translational Therapeutics of "Classical” HDAC to "Hybrid” HDAC Inhibitors. Euro. J. Med. Chem. 2021, 209, 112844. (I.F. 7. 08).
7. Shyam Kumar Lokhande†, Gargi Nikhil Vaidya†, Sanjeev Kumar, Dinesh Parshuram Satpute, Ashwini Venkatesh, Dinesh Kumar.* L-Aspartic Acid (L-Asp): A Sustainable Alternative of Phosphine Ligands for the Chemo- and Regioselective Indole C–H Arylation. Adv. Synth. Catal. 2020, 362, 2857-2863. († equal first author) (IF = 5.98).
8. Sanjeev Kumar†, Dinesh Parshuram Satpute†, Gargi Nikhil Vaidya†, Mithilesh Nagpure, Deepak Kumar Meena, Shyam Kumar Lokhande, Dinesh Kumar.* Sustainable Synthesis and Functionalization of Indolylbenzothiazoles, Tetrahedron Lett. 2020, 61, 152017-152020. († equal first author) (IF = 2.03).
9. Gargi Nikhil Vaidya, Sneha Fiske, Hansa Verma, Shyam Kumar Lokhande and Dinesh Kumar.* A Micellar Catalysis Strategy Applied to Pd-Catalyzed C-H Arylations of Indoles in Water. Green Chem. 2019, 21, 1448-1454. (I.F. 11.03). Highlighted in OPRD under section "Green Chemistry Article of Industrial Interest”
10. Gargi Nikhil Vaidya, Arif Khan, Hansa Verma, Sanjeev Kumar and Dinesh Kumar.* Structure Ligation Relationship of Amino Acids for the Amination Cross-Coupling Reactions. J. Org. Chem. 2019, 84, 3004-3010. (I.F. 4.19). Highlighted in Organic Research Portal under N-Arylation.