Dr. RajaSekhar Reddy Alavala

Qualification              : PhD

Specialization             : Pharmaceutical Chemistry

E mail                         : alavala.rajasekharreddy@nmims.edu

Phone                         : 022-42332000 (Extn-2020)

Experience                 : 13.5 (Academics – 10.5 years, Research – 3 years)

Brief Bio: Dr. Rajasekhar Reddy Alavala, working as an Assistant Professor in the Department of Pharmaceutical Chemistry, SPPSPTM. Previously worked as an Associate Professor at K L College of Pharmacy, KLEF Deemed to be University, Guntur. He pursued B.Pharm. and M.Pharm. (Pharm. Chemistry) from Kakatiya University and received Doctorate degree from JNTU Hyderabad. He secured 96 percentile in GATE-PY 2009 conducted by IIT Kharagpur. He received several awards and also a recipient of DST fellowship. He has 11 years of academic and research experience. To his credit he has published 83 research and review articles in peer-reviewed national and international journals with highest impact of 6.321. He participated in more than 48 national and international conferences/seminars/symposia/ workshops/FDP’s and presented 18 research papers. Got trained from IIT Bombay for implementing ICT enabled modern teaching methodologies. He is an editorial board member of various scientific journals and acting as a scientific reviewer for peer-reviewed journals. He has guided 3 post graduate students and 10 graduate students for their projects. He has guided the students to present 25 paper presentations in various conferences/seminars, among them 9 papers got best presentation award from different Institutions including Acharya Nagarjuna University.

Interest areas:

• Small molecule synthesis
• Natural Product Research
• Molecular modelling – Molecular Dynamic Simulations, 2D & 3D-QSAR modeling
• Alzheimer’s Disease therapeutics
• Anticancer drug research

Research:

• Publications – 83 (International - 79, National - 4)
• Books - Nil
• Book Chapters - 5
• Patents – 3 (Published – 3, Granted – 0)
• Presentations- 25 (International - 07, National - 18)
• Government funded projects – 01
  • Ongoing: Co-Principal Investigator - Science Technology and Innovation (STI) Hub in Guntur District (KLEF), Andhra Pradesh (DST/SEED/SCSP/STI/2021/699/G, INR. 2.59 Crores).
• Industry projects
  • Completed: 01

Consultancy project on Synthesis of Curcumin-Metal complexes as possible antimicrobial agents, worth of Rs. 50,000 for MYBO Group, Visakhapatnam.

• Ongoing: Nil

• University funded project- Total – 01

Completed an internal funding project on Synthesis of Gentiobiose derived Amygdalin analogues for possible antiviral activity, Rs. 2 Lakhs seed money from KLEF Deemed to be University, Guntur, A.P.

Conferences/Workshops/Seminars attended – 48; Organized - 07

Academic activities

He has guided 06 M. Pharm. Students for their research projects. Three (One Fulltime and Two Part-time) candidates are registered for Ph.D. under his supervision. 

Awards:

• Received Best Teacher Award for the academic year 2020-21 from K L E F (Deemed to be University), Guntur, A.P., India
• Received Best Teacher Award for the academic year 2019-20 from K L E F (Deemed to be University), Guntur, A.P., India.
• Quality Contributions as an Associate Professor (2018-2019), Internal Quality Assurance cell (IQAC), K L E F (Deemed to be University), Guntur
• Senior Research Fellow (Dec 2011 – Nov 2014), in a Department of Science & Technology, New Delhi funded project (DST Number:SR/FT/CS-114/2010(G)).
• Secured 94.58 percentile (Score 442) in GATE-2009 (National level entrance for admission into M. Pharmacy)
• Received AICTE (All India Council for Technical Education) Fellowship during M. Pharmacy

Professional Memberships

• Registered Pharmacist, Andhra Pradesh State Pharmacy Council
• Life Member, MYBO Group
• Member, American Chemical Society (ACS) (31180167, Category-Community Member)
• Member, National Science Teaching Association (ID Number - 2475920)
• Life Member, World Economics Association

Recent Publications

1. Nachiket Joshi, Alavala Rajasekhar Reddy, Sulfonamido, Amido Heterocyclic Adducts of Tetrazole Derivatives as BACE1 Inhibitors – In Silico Exploration Research, Molecular Diversity,  2024 https://doi.org/10.1007/s11030-023-10792-7 (Impact factor: 3.2).
2. Sowmya Andole, Gouthami Thumma, Rajasekhar Reddy Alavala & Kiran Gangarapu, Field-based 3D-QSAR for tyrosine protein kinase JAK-2 inhibitors, Journal of Biomolecular Structure and Dynamics, 42, 10, 2024, 5321-5333, https://doi.org/10.1080/07391102.2023.2226723. (Impact factor: 4.4)
3. Samin A. Shaikh, Satish N. Wakchaure, Shivaji R. Labhade, Raju R. Kale, Rajasekhar R. Alavala, Santosh S. Chobe, Synthesis, biological evaluation, and molecular docking of novel 1,3,4-substituted-thiadiazole derivatives as potential anticancer agent, BMC Chemistry, 18, 119 (2024). https://doi.org/10.1186/s13065-024-01196-1 (Impact factor: 4.4)
4. Narsaiah Chelimela, Rajasekhar Reddy Alavala, Shobha Rani Satla, Curcumin – Bioavailability Enhancement by Prodrug Approach and Novel Formulations, Chemistry & Biodiversity, 21 (5), 2024, e202302030, https://doi.org/10.1002/cbdv.202302030 (Impact factor: 2.3)
5. Shlok Bodke, Nachiket Joshi, Rajasekhar Reddy Alavala, Divya Suares, In silico exploration of CB2 receptor agonist in the management of neuroinflammatory conditions by pharmacophore modelling, Computational Biology and Chemistry, 110, 2024, 108049. https://doi.org/10.1016/j.compbiolchem.2024.108049 (Impact factor: 3.1)
6. Vernekar, Siddhi; Budha, Roja Rani; Alavala, Rajasekhar Reddy, Radiopharmaceuticals: A New Vista for Diagnosis and Treatment of Thyroid Cancer, Current Radiopharmaceuticals, 17 (2), 2024, 148-162, https://doi.org/10.2174/0118744710277275231112081003 (Impact factor: 2.3)
7. Nachiket Jitendra Joshi, Alavala Raja Sekhar Reddy, Navigating the GSK-3β inhibitors as versatile multi-target drug ligands in Alzheimer’s disease intervention – A comprehensive review, Results in Chemistry, 7, 2024, 101500, https://doi.org/10.1016/j.rechem.2024.101500 (Impact factor: 2.9)
8. Michelyne Haroun, Santosh S Chobe, Rajasekhar Reddy Alavala et al, 1, 5-Benzothiazepine Derivatives: Green Synthesis, In Silico and In Vitro Evaluation as Anticancer Agents, Molecules, 2022, 27(12), 3757; https://doi.org/10.3390/molecules27123757. (Impact factor: 4.927)
9. Umasankar Gorla, GSN Koteswara Rao, Kulandaivelu Umasankar, Alavala Rajasekhar Reddy, Panda Siva Prasad, Lead Finding from Selected Flavonoids with Antiviral (SARS-CoV-2) Potentials against COVID-19: An in-silico Evaluation, Combinatorial Chemistry & High Throughput Screening, 2021; 24(6): 879-890. https://doi.org/10.2174/1386207323999200818162706 (Impact factor: 2.5).
10. Rasool, Sahibzada Tasleem, Rajasekhar Reddy Alavala, Umasankar Kulandaivelu, and Nagaraja Sreeharsha. 2020. "Non-Invasive Delivery of Nano-Emulsified Sesame Oil-Extract of Turmeric Attenuates Lung Inflammation" Pharmaceutics, 2020, 12 (12), 1206. https://doi.org/10.3390/pharmaceutics12121206. (Impact factor: 4.421).
11. Rajesh Kumar Chawla, G.S.N. Koteswara Rao, Umasankar Kulandaivelu, Siva Prasad Panda and Rajasekhar Reddy Alavala, A Selective and Sensitive Method Development and Validation of 1,1-Dimethyl-3-HydroxyPyrrolidinium Bromide Impurity in Glycopyrrolate Oral Solution by Liquid Chromatography–Tandem Mass Spectroscopy, Journal of Chromatographic Science, 2021, 1–10, bmab003, https://doi.org/10.1093/chromsci/bmab003 (Impact factor:1.682).
12. Sahibzada Tasleem Rasool, Rajasekhar Reddy Alavala, Umasankar Kulandaivelu and Nagaraja Sreeharsha, Non-Invasive Delivery of Nano-Emulsified Sesame Oil-Extract of Turmeric Attenuates Lung Inflammation, Pharmaceutics 2020, 12, 1206; https://doi:10.3390/pharmaceutics12121206 (Impact factor: 4.441).