Dr. Kalyani Barve

Qualification : M. Pharm., Ph.D _Tech.

Specialization : Pharmacology, Pharmacognosy

E mail : kalyani.barve@nmims.edu

Phone : 022-42332000 (Extn-2025) 

Experience : Academics-15 years

She has been teaching undergraduate and post graduate students, subjects like pharmacology, pharmacognosy, pathophysiology and anatomy and physiology and has executed research projects in areas of inflammation, neuropharmacology, cardiovascular pharmacology, diabetes &diabetic complications, toxicology, pharmacokinetics and bioavailability and bioequivalence studies.

Interest areas:

• Targeting inflammatory pathways for therapeutic management of cardiovascular/metabolic/CNS disorders.
• Preclinical evaluation of medicines used in traditional systems (Ayurveda, Siddha, Homeopathy and Unani) used in cardiovascular and metabolic disorders.
• Study of Pharmacodynamic interactions of herbs and medicines
• Extraction and isolation of phytoconstituents 

Research

• Publications – 42 (International- 29 , National- 13 )
• Books- 2
• Book Chapters- 08
• Patents- 01
• Presentations- 18(International- nil , National- 18)

Research grants-06(Government + University)

Government funded projects – 2

• Completed (Preclinical studies on Triphala for its possible effects in the treatment of microvascular diabetic complications) funded by Ministry of AYUSH, 36,64,780/- (Co-investigator)
• Ongoing (Topical formulations of Garcinia indica extract for treatment of allergic contact dermatitis) funded by Rajiv Gandhi Science and Technology commission, Government of Maharashtra, 17,23,920/- (Principal investigator) 

University funded project-04

• Completed ("Investigating the role of garcinol enriched fraction in the treatment of atherosclerosis) funded by SVKM’s NMIMS (Deemed to be University), Mumbai. Rs.1,00,000/- (Principal Investigator).
• Ongoing (Exploring the role of 7 hydroxyfrullanolide in the treatmentof epilepsy) funded by SVKM’s NMIMS (Deemed to be University), Mumbai. Rs.1,00,000/- (Principal Investigator).
• Ongoing (Investigation on the Inclusion Chemistry Approach for Pterostilbene in Postmenopausal Osteoporosis) funded by SVKM’s NMIMS (Deemed to be University), Mumbai. Rs.1,00,000/- (Principal Investigator).
• Ongoing (Exploring the role of trans-anethole in neuroinflammation induced Alzheimers disease rodent model by suppressing NLRP3 inflammosome pathway) funded by SVKM’s NMIMS (Deemed to be University), Mumbai. Rs.1,00,000/- (Co- Investigator).

Conferences/Workshops/Seminars attended: 23

Academic activities

She has guided 31 M.Pharm. students for their major and minor research projects.

Awards

• Silver medal in Essay competition held by Shri B.V.Patel Education Trust on Role of Pharmaceutical Research Scientist and Industry in the Pandemic,2022
• First prize in poster session at 8th International Congress of Society for Ethnopharmacology on "Ethnopharmacology & Medicinal Plants - Approach Towards Product Development.” held at Poona College of Pharmacy, Bharti Vidyapeeth, Pune, India, 2021.
• First prize in oral session at Update Ayurveda 2014 conference held at Nair hospital in Mumbai.
• Best faculty award at SPTM for the year 2010-2011.
• University gold medal for B. Pharm
• IDMA-G.P. Nair award for B. Pharm
• Award from M.S.U. Pharmacy Alumni Association for securing first rank in B. Pharm

Professional Memberships

• Indian Pharmacological Society (IPS)-Life member
• Indian Pharmaceutical Association (IPA)-Life member
• Association of Pharmacy Teachers of India (APTI)-Life member
• International Academy of Cardiovascular Sciences (IACS-India section)-Life member
• Indian Society of Hypertension- Life member

Recent Publications

P Shah, M Lalan, K Barve. Intranasal delivery: An attractive route for the administration of nucleic acid based therapeutics for CNS disorders Frontiers in pharmacology.2022;13: 974666. 2022. https://doi.org/10.3389/fphar.2022.974666. (IF=5.81)

Jain K, Barve K, Bhatt LK. Gasdermins: Pore-forming Proteins as a Potential Therapeutic Target. Curr Protein Pept Sci. 2022; 23(3):133-151. doi: 10.2174/1389203723666220510123740. PMID: 35538820. (IF=3.272)

Alina Furniturewalla, Kalyani Barve. Approaches to overcome bioavailability inconsistencies of epigallocatechin gallate, a powerful anti-oxidant in green tea,Food Chemistry Advances,Volume 1,2022,100037, https://doi.org/10.1016/j.focha.2022.100037.

Suryavanshi SV, Barve K, Utpat SV, Kulkarni YA. Triphala churna ameliorates retinopathy in diabetic rats. Biomed Pharmacother. 2022 Apr;148:112711. doi: 10.1016/j.biopha.2022.112711. Epub 2022 Feb 12. PMID: 35168075. (IF=6.529)

Lalan, M., Shah, P., Barve, K. et al. Skin cancer therapeutics: nano-drug delivery vectors—present and beyond. Futur J Pharm Sci 7, 179 (2021). https://doi.org/10.1186/s43094-021-00326-z

Suryavanshi SV, Barve K, Addepalli V, Utpat SV, Kulkarni YA. Triphala Churna-A Traditional Formulation in Ayurveda Mitigates Diabetic Neuropathy in Rats. Front Pharmacol. 2021 Jun 3;12:662000. doi: 10.3389/fphar.2021.662000. PMID: 34149415; PMCID: PMC8211421. (IF: 5.81)

Book chapter

Alina Furniturewalla and Kalyani Barve. Marine antioxidants in the management of atherosclerosis In: Se-Kwon Kim (eds)Marine antioxidants: preparations, synthesis and applications. Academic Press 2022

Bhatt L.K., Gokani S., Barve K. Colon Cancer Stem Cells In: Chakraborti S. (eds) Handbook of Oxidative Stress in Cancer: Therapeutic Aspects.Springer, Singapore. 2022