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Dr. Yogesh Anant Kulkarni

Dr. Yogesh Anant Kulkarni

Associate Professor, Associate Dean, Section Head, Pharmacognosy

Specialization

Pharmacognosy, Pharmacology
M. Pharm., Ph.D.

Email Id

yogesh.kulkarni@nmims.edu

Phone No.

+91-022-42332000 (Extn- 2038)

Experience

15 years

Interest areas: 

  • Phytopharmacology focusing on diabetes, diabetic complications, inflammation and nociception.
  • Toxicity of natural products
  • Standardization of natural products
  • Herbal formulations and cosmetics

Research

  • Publications – 75 (International- 66, National- 09)
  • Books- 09
  • Book Chapters- 21
  • Patent- 01
  • Presentations- 74 (International- 53, National-21)

Research grants – 18 (Government+ University+ Industry)

 

Government funded projects – Total 03

Completed- 02

  • "Effect of B. varegata (Caesalpiniaceae): a phytomedicine in diabetes and its complications” funded by Department of Science & Technology (DST), Govt. of India, Rs. 35 lakhs. (Principal Investigator). 
  • "Development of Model for Non Alcoholic Fatty Liver Disease Based on Ayurvedic Principles” funded by Department of AYUSH, Govt. of India. Rs. 5 lakhs. (Co-Investigator).

Ongoing-01

  • "Preclinical Studies on Triphala for its Possible Effects in Treatment of Microvascular Complications of Diabetes” funded by Ministry of AYUSH, Govt. of India. Rs. 36.64 lakhs. (Principal Investigator).

 

University funded project- Total-01

Completed-01

"Targeting TGF β Pathway with Combination Of Drugs for Management of Diabetic Nephropathy: A Serious Complication of Diabetes” funded by SVKM’s NMIMS (Deemed to be University), Mumbai. Rs.52000/- (Principal Investigator).

 

Industry Research Projects -  Total 14

Completed- 12

  • Dissolution study of Adipomimetin in Sabouraud’s Chloramphenicol medium.
  • Acute toxicity study of herbomineral formulation.
  • Effect of herbal formulation on selective reproductive hormones in experimental animals.
  • SDS Page profiling of heat stable protein fractions from plants.
  • Characterization of heat stable proteins fractions from plants by SDS Page profiling and by their sensitivity against microorganism.
  • Effect of herbal formulation on hormone level in azoospermia.
  • Pharmacokinetic profiling of semisynthetic molecule.
  • Pharmacological evaluation of herbal formulation for treatment of azoospermia.
  • To study effect of long term treatment of herbal drug in animal model of chronic renal failure.
  • Evaluation of herbal drug against chronic renal failure in rats.
  • Memory enhancing activity of plant extracts in rat model.
  • Evaluation of some actives & polyherbal formulations for hair growth promoting activity (Pilot Study).

Ongoing- 02

  • To study cardioprotective effect of herbomineral formulations in experimental animals.
  • Standardisation of SP-Max formulation.

 

Conferences/Workshops/Seminars attended- 66

Academic activities

He has guided 40 M. Pharm. students for their research projects.

Two student has successfully completed PhD under his guidance.

Five candidates are registered for PhD under his supervision.

Awards

  • Received Best Research Output Award (Year 2015-2016), SVKM’s NMIMS (Deemed to be University), SPP School of Pharmacy & Technology Management, Mumbai.
  • Received travel grant from Science & Engineering Research Board (SERB), Govt. of India for attending conference Pharmacology 2014 organized by British Pharmacological Society, London, UK.
  • Guest edited a Special Issue for the journal "Pharmaceutical Crops” by Bentham Science Publishers. The theme of the special issue was "Diabetes, Diabetic Complications and Natural Products”. The issue was published in November 2014.
  • Received Best Faculty Award for the year 2012-2013 from SVKM’s NMIMS, Mumbai.
  • Received INSPIRE Faculty Award 2012 from Department of Science & Technology (DST), Govt. of India.
  • Selected by the American Biographical Institute for Sir Isaac Newton Scientific Award of Excellence For 2012.
  • Admitted as Fellow of Academy of Sciences for Animal Welfare in 2012.
    The academy of Sciences for Animal Welfare is working for prevention of cruelty, enhancement of animal health and use of minimum animals for Research & Development. The academy is approved body of Animal Welfare Board which is under Ministry of Environment and Forests, Govt. of India.
  • Listed as Member (Biography) of MARQUIS Who's Who in the World 2012, USA.
  • Invited as Chairperson for Symposium : Pharmacotherapeutics of hypertension   at BPCON 2012, 22nd Annual Conference of Indian Society of Hypertension, Mumbai.The Symposium  was sponsored by Abbott pvt. Ltd. 
  • Received grant under "International Travel Support Scheme” from "Department of Science & Technology (DST), Govt. of India” under Young Scientist category for attending Experimental Biology 2011 at Washington DC, USA, 
  • Received travel grant from "All India Council of Technical Education (AICTE)”, New Delhi, India” for attending  29th Annual meeting of American College of Toxicology, Tucson, Arizona, USA. 
  • Received "Sir Ratan Tata Trust Scholarship”.
  • Received scholarship for Post Graduate Studies from "All India Council of Technical Education (AICTE)”, New Delhi, India.

Professional Memberships

  • American Society of Pharmacology & Experimental Therapeutics (ASPET), USA
  • British Pharmacological Society, UK.
  • American College of Toxicology (ACT), USA.
  • Indian Pharmacological Society (IPS)-Life Member
  • Society of Toxicology, India (STOX)-Life Member
  • Association of Pharmaceutical Teachers of India (APTI)- Life Member
  • Laboratory Animal Scientist’s Association (LASA), India- Life Member
  • Association of Toxicology (AoT), India- Life Member
  • Indian Pharmacist’s Association- Life Member
  • Nutrition Society of India, Life Member
  • Indian Society of Pharmacognosy (ISP)- Life Member

Recent Publications

  • Ankit P. Laddha, Vivek V. Nalawade, Milind Gharpure and Yogesh A. Kulkarni (2020). Development and Validation of HPLC Method for Determination of Sodium Copper Chlorophyllin – A Food Colorant and Its Application in Pharmacokinetic Study. Chemistry & Biodiversity. 17 (8), e2000223. (Impact factor- 2.039)
  • DOI: https://doi.org/10.1002/cbdv.202000223
  • Ojaskumar D. Agrawal, Yogesh A. Kulkarni (2020). Mini-review of analytical methods used in quantification of ellagic acid. Reviews in Analytical Chemistry. 39: 31–44. (Impact factor- 2.174)
  • DOI: https://doi.org/10.1515/revac-2020-0113
  • Rohan Khair, Pravin Shende, Yogesh A. Kulkarni (2020). Nanostructured polymer-based cochleates for effective transportation of insulin. Journal of Molecular Liquids. 311, 113352. (Impact factor- 5.065)
  • DOI: https://doi.org/10.1016/j.molliq.2020.113352
  • Sachin V. Suryavanshi, Yogesh A. Kulkarni (2020). Escin alleviates peripheral neuropathy in streptozotocin induced diabetes in rats. Life Sciences. 254, 117777.
  • (Impact factor- 3.647)
  • DOI: https://doi.org/10.1016/j.lfs.2020.117777
  • Ankit P. Laddha, Yogesh A. Kulkarni (2020). NADPH oxidase: A membrane-bound enzyme and its inhibitors in diabetic complications. European Journal of Pharmacology. 881 (2020) 173206. (Impact factor- 3.263)
  • DOI: https://doi.org/10.1016/j.ejphar.2020.173206
  • Yogesh A. Kulkarni, Ankit P. Laddha (2020). Bauhinia variegata leaf extract: An effective management option for diabetic cardiomyopathy. South African Journal of Botany. 132, 50-58. (Impact factor- 1.792)
  • DOI: https://doi.org/10.1016/j.sajb.2020.04.021
  • Shreeya V. Deshmukh, Bala Prabhakar, Yogesh A. Kulkarni (2020). Water soluble vitamins and their role in diabetes and its complications. Current Diabetes Reviews. 16, 649-656.
  • DOI : https://doi.org/10.2174/1573399815666190916114040
  • Pooja Dhileepkumar Rao, Himanshu Sankrityayan, Anjali Srivastava, Yogesh A. Kulkarni, Shrikant R. Mulay and Anil Bhanudas Gaikwad (2020). PARP’ing fibrosis: repurposing poly (ADP ribose) polymerase (PARP) inhibitors. Drug Discovery Today 25(7). 1253-1261. (Impact factor- 7.321)
  • DOI: https://doi.org/10.1016/j.drudis.2020.04.019
  • Kaveri M. Adki, Yogesh A. Kulkarni (2020). Chemistry, pharmacokinetics, pharmacology and recent novel drug delivery systems of paeonol. Life Sciences 250, 117544. (Impact factor- 3.647)
  • DOI: https://doi.org/10.1016/j.lfs.2020.117544
  • Manisha J. Oza and Yogesh A. Kulkarni (2020). Formononetin Ameliorates Diabetic Neuropathy by Increasing Expression of SIRT1 and NGF. Chemistry & Biodiversity. 17(6): (Impact factor- 2.039)
  • DOI: https://doi.org/10.1002/cbdv.202000162
  • Manisha J. Oza, Yogesh A. Kulkarni (2020). Formononetin alleviates diabetic cardiomyopathy by inhibiting oxidative stress and upregulating SIRT1 in rats. Asian Pacific Journal of Tropical Biomedicine. 10(6): 254-262. (Impact factor- 1.903)
  • DOI: https://doi.org/10.4103/2221-1691.283939
  • Ankit Pravin Laddha , Yogesh Anant Kulkarni (2020). Daidzein Attenuates Kidney Damage in Diabetic Rats. The FASEB Journal .34 (S1), 05292. (Impact factor- 5.391)
  • DOI: https://doi.org/10.1096/fasebj.2020.34.s1.05292
  • Manisha J. Oza and Yogesh A. Kulkarni (2020). Trifolium pratense (Red Clover) Improve SIRT1 Expression and Glycogen Content in High Fat Diet-Streptozotocin Induced Type 2 Diabetes in Rats. Chemistry & Biodiversity. 17(4):e2000019. (Impact factor- 1.449)
  • DOI: https://doi.org/10.1002/cbdv.202000019
  • Sankrityayan, M.J.Oza, Y.A.Kulkarni, S.R.Mulay, A.B. Gaikwad (2019). ER stress response mediates diabetic microvascular complications. Drug Discovery Today. 24 (12), 2247-2257. (Impact factor- 6.880)
  • DOI: https://doi.org/10.1016/j.drudis.2019.08.003
  • Marina Raju, Yogesh A. Kulkarni, Sarika Wairkar (2019). Therapeutic potential and recent delivery systems of berberine: A wonder molecule. Journal of Functional Foods. 61: 103517. (Impact factor- 3.197)  DOI: https://doi.org/10.1016/j.jff.2019.103517
  • Sandip T. Auti and Yogesh A. Kulkarni (2019). Acute and 28 day repeated dose oral toxicity study of caraway oil in rats. Drug Metabolism and Personalized Therapy. 34 (3), 20190011. DOI: https://doi.org/10.1515/dmpt-2019-0011
  • Ankit P. Laddha, Yogesh A. Kulkarni (2019). VEGF and FGF-2: Promising targets for the treatment of respiratory disorders. Respiratory Medicine. 156:33-46. (Impact factor- 3.237) DOI: https://doi.org/10.1016/j.rmed.2019.08.003

BOOK CHAPTERS

  • Kaveri M. Adki, Ankit P. Laddha, Anil B. Gaikwad, and Yogesh A. Kulkarni (2020). Potential Role of Seeds from India in Diabetes. In: Nuts and Seeds in Health and Disease Prevention. Second Edition. Academic Press: Elsevier, USA. Pp-365-391.
  • DOI: https://doi.org/10.1016/B978-0-12-818553-7.00026-7 , ISBN: 978-0-12-818553-7
  • Ankit P. Laddha, Kaveri M. Adki, Anil B. Gaikwad, and Yogesh A. Kulkarni (2020). Beneficial Effects of Nuts From India in Cardiovascular Disorders. In: Nuts and Seeds in Health and Disease Prevention. Second Edition. Academic Press: Elsevier, USA. Pp-453-469.
  • DOI: https://doi.org/10.1016/B978-0-12-818553-7.00032-2 , ISBN: 978-0-12-818553-7
  • Manisha J. Oza, Sachin V. Suryavanshi, Mayuresh S. Garud, Sandip T. Auti, Ankit P. Laddha and Yogesh A. Kulkarni. (2019). Molecular Targets of Angiogenesis and Future Potential of Anti-angiogensis Therapy in Multiple Sclerosis. In: Anti-Angiogenesis Drug Discovery and Development. Volume 4. Bentham Science Publishers. Pp-137-161
  • DOI: https://doi.org/10.2174/97816810839711170401 , eISBN: 978-1-68108-397-1, 2019; ISBN: 978-1-68108-398-8; ISSN: 2452-3240 (Print); ISSN: 2210-268X (Online)
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