Dr. Yogesh Kulkarni

1. Dissolution study of Adipomimetin in Sabouraud’s Chloramphenicol medium.

14. Acute toxicity study of herbomineral formulation.
15. Effect of herbal formulation on selective reproductive hormones in experimental animals.
16. SDS Page profiling of heat stable protein fractions from plants.

1. Characterization of heat stable proteins fractions from plants by SDS Page profiling and by their sensitivity against microorganism.

18. Effect of herbal formulation on hormone level in azoospermia.

1. Pharmacokinetic profiling of semisynthetic molecule.

20. Pharmacological evaluation of herbal formulation for treatment of azoospermia.
21. To study effect of long term treatment of herbal drug in animal model of chronic renal failure.

1. Evaluation of herbal drug against chronic renal failure in rats.
2. Memory enhancing activity of plant extracts in rat model.
3. Evaluation of some actives & polyherbal formulations for hair growth promoting activity (Pilot Study).

Ongoing- 04

1. Preclinical studies on a nutraceutical product for management of Alzheimer’s disease.
2. Pharmacokinetic study of oral formulations.
3. Effect of herbal formulation on antimullerian hormone and some biochemical parameters.
4. Exploring potential of herbomineral formulation in diabetic complications.

Conferences/Workshops/Seminars attended- 68

Academic activities

He has guided 42 M. Pharm. students for their research projects.

05 students have successfully completed PhD under his guidance.

Six candidates are registered for PhD under his supervision.

RECENT PUBLICATIONS

1. Adki KM and Kulkarni YA (2022). Paeonol attenuates retinopathy in streptozotocin-induced diabetes in rats by regulating the oxidative stress and polyol pathway. Frontiers in Pharmacology. 13:891485. (Impact factor- 5.988)

DOI: https://doi.org/10.3389/fphar.2022.891485

2. UM Parmar, MP Jalgaonkar, YA Kulkarni, MJ Oza (2022). Autophagy-nutrient sensing pathways in diabetic complications. Pharmacological Research, 184, 106408. (Impact factor- 10.334)

DOI: https://doi.org/10.1016/j.phrs.2022.106408

3. Pranali B. Yeram and Yogesh A. Kulkarni (2022). Glycosides and Vascular Complications of Diabetes. Chemistry & Biodiversity. 19 (10), e202200067. (Impact factor- 2.745)

DOI: https://doi.org/10.1002/cbdv.202200067

4. Khairnar, S.I., Kulkarni, Y.A. & Singh, K. (2022). Cardiotoxicity linked to anticancer agents and cardioprotective strategy. Archive of Pharmacal Research 45, 704–730 DOI: https://doi.org/10.1007/s12272-022-01411-4 (Impact factor-6.010)
5. Ankit P. Laddha, Yogesh A. Kulkarni. (2022). Daidzein attenuates urinary bladder dysfunction in streptozotocin‑induced diabetes in rats by NOX‑4 and RAC‑1 inhibition.

Naunyn-Schmiedeberg's Archives of Pharmacology. 395: 975–986.

DOI: https://doi.org/10.1007/s00210-022-02246-y

6. Shreya R. Savla, Ankit P. Laddha & Yogesh A. Kulkarni (2021). Pharmacology of apocynin: a natural acetophenone. Drug Metabolism Reviews. 53 (4), 542-562. (Impact factor- 3.956) DOI: https://doi.org/10.1080/03602532.2021.1895203
7. M Raju, SS Kunde, ST Auti, YA Kulkarni, S Wairkar (2021). Berberine loaded nanostructured lipid carrier for Alzheimer's disease: Design, statistical optimization and enhanced in vivo performance. Life Sciences, 285, 119990. (Impact factor- 5.037) DOI: https://doi.org/10.1016/j.lfs.2021.119990
8. Ankit P Laddha, Yogesh A Kulkarni (2021). Daidzein mitigates myocardial injury in streptozotocin-induced diabetes in rats. Life Sciences. 284, 119664. (Impact factor- 5.037) DOI: https://doi.org/10.1016/j.lfs.2021.119664
9. R Joshi, AP Laddha, YA Kulkarni, S Wairkar (2021). Improved performance of naringenin herbosomes over naringenin in streptozotocin-induced diabetic rats: In vitro and in vivo evaluation. Asian Pacific Journal of Tropical Biomedicine 11 (9), 385-393. (Impact factor- 1.55) DOI: https://doi.org/10.4103/2221-1691.321131
10. Suryavanshi SV, Barve K, Addepalli V, Utpat SV and Kulkarni YA (2021) Triphala Churna—A Traditional Formulation in Ayurveda Mitigates Diabetic Neuropathy in Rats. Frontiers in 12:662000. (Impact factor-4.225)

DOI: https://doi.org/10.3389/fphar.2021.662000

11. Manisha J. Oza, Ankit P. Laddha, Anil Bhanudas Gaikwad, Shrikant R. Mulay, Yogesh A. Kulkarni. (2021). Role of dietary modifications in the management of type 2 diabetic complications. Pharmacological Research. 168; 105602. (Impact factor- 5.893) DOI: https://doi.org/10.1016/j.phrs.2021.105602
12. Kaveri M. Adki, Yogesh A. Kulkarni (2021). Neuroprotective effect of paeonol in streptozotocin-induced diabetes in rats. Life Sciences. 271, 119202. (Impact factor- 3.647) DOI: https://doi.org/10.1016/j.lfs.2021.119202
13. Ankit P. Laddha, Yogesh A. Kulkarni (2021). Daidzein ameliorates diabetic retinopathy inexperimental animals. Life Science. 265, 118779. (Impact factor- 3.647) DOI: https://doi.org/10.1016/j.lfs.2020.118779 .
14. Yogesh A. Kulkarni, Sachin V. Suryavanshi (2021). Combination of naringenin and lisinopril ameliorates nephropathy in Type-1 diabetic rats. Endocrine Metabolic & Immune Disorders-Drug Targets. 21: 173-182. (Impact factor- 1.973) DOI: https://doi.org/2174/1871530320666200516163919
15. Kaveri M. Adki, S. Murugesan, Yogesh A. Kulkarni (2020). In Silico and In Vivo Toxicological Evaluation of Paeonol. Chemistry & Biodiversity. 17, e2000422. (Impact factor- 2.039)

DOI: https://doi.org/10.1002/cbdv.202000422

16. Kaveri M Adki, Yogesh A Kulkarni. Potential Biomarkers in Diabetic Retinopathy (2020). Current Diabetes Reviews ;16(9):971-983.

DOI: https://doi.org/10.2174/1573399816666200217092022

17. Sachin V. Suryavanshi, Mayuresh S. Garud, Kalyani Barve, Addepalli V., Sachin V. Utpat, Yogesh A. Kulkarni. (2020) Triphala Ameliorates Nephropathy via Inhibition of TGF-β1 and Oxidative Stress in Diabetic Rats. Pharmacology.;105(11-12):681-691. (Impact factor- 1.6) DOI: https://doi.org/10.1159/000508238 .
18. Niharika Shiva, Nisha Sharma, Yogesh A. Kulkarni, Shrikant R. Mulay, Anil Bhanudas Gaikwad (2020). Renal ischemia/reperfusion injury: An insight on in vitro and in vivo models. Life Sciences. 256:117860. (Impact factor- 3.647)

DOI: https://doi.org/10.1016/j.lfs.2020.117860

Book Chapters

1. Ojaskumar D. Agrawal, Yogesh A. Kulkarni (2022). Phytochemistry and Pharmacology of Terminalia chebula: An Update (2022).Chemistry inside spices & herbs: research & development, Volume 2. Bentham "ISBN: 978-1-68108-950-8 (Print), ISBN: 978-1-68108-949-2 (Online)" Pages-229-260.

DOI: https://doi.org/10.2174/9781681089492122020012

2. Yogesh Kulkarni (2022). "Antidiabetic drugs” In: Textbook of Pharmacology Thieme Medical and Scientific Publishers. ISBN 978-93-90553-15-0
3. Ankit P. Laddha, Yogesh A. Kulkarni. (2022). Vascular Endothelial Growth Factor and Inflammatory Airway Diseases: An Update, Editor(s): Sam M Janes, Encyclopedia of Respiratory Medicine (Second Edition), Academic Press, Pages 401-408.

ISBN 9780081027240,

DOI: https://doi.org/10.1016/B978-0-08-102723-3.00211-0

4. Ankit P. Laddha, Anil B. Gaikwad, Yogesh A. Kulkarni (2021). Receptors | Structural and Functional Insights of VEGF and Its Receptors, Editor(s): Joseph Jez, Encyclopedia of Biological Chemistry III (Third Edition), Elsevier, Pages 286-293. ISBN 9780128220405. DOI: https://doi.org/10.1016/B978-0-12-819460-7.00131-6
5. Malek V., Suryavanshi S.V., Sharma N., Kulkarni Y.A., Mulay S.R., Gaikwad A.B. (2021) Potential of Renin-Angiotensin-Aldosterone System Modulations in Diabetic Kidney Disease: Old Players to New Hope!. In: Reviews of Physiology, Biochemistry and Pharmacology. Springer, Cham. Vol 179, pp 31-71. (Impact factor- 5.545) DOI: https://doi.org/10.1007/112_2020_50
6. Adki K.M., Kulkarni Y.A. (2021). Glycosides from Natural Sources in the Treatment of Diabetes Mellitus. In: Structure and Health Effects of Natural Products on Diabetes Mellitus. Springer, Singapore. Pp-81-102.

DOI: https://doi.org/10.1007/978-981-15-8791-7_5

7. Laddha A.P., Kulkarni Y.A. (2021). Nitrogenous Compounds from Plant Origin in Management of Diabetes Mellitus. In: Structure and Health Effects of Natural Products on Diabetes Mellitus. Springer, Singapore. Pp 235-249.

DOI: https://doi.org/10.1007/978-981-15-8791-7_13

8. Laddha A.P., Adki K.M., Oza M.J., Gaikwad A.B., Kulkarni Y.A. (2020). Medicinal Plants from Genus Costus in the Management of Diabetes. In: Phytotherapy in the Management of Diabetes and Hypertension. Volume: 4. Bentham Science Publishers, Singapore. 100-118.

DOI: https://doi.org/10.2174/9789811480515120040006

9. Agrawal O.D., Kulkarni Y.A. (2020). Management of Diabetes Mellitus by Natural Products: Glucagon-like Peptide 1 Perspective In: Phytotherapy in the Management of Diabetes and Hypertension. Volume: 3. Bentham Science Publishers, Singapore. 95-126.

DOI: https://doi.org/10.2174/9789811459139120030006

10. Adki K.M., Laddha A.P., Oza M.J., Gaikwad A.B., Kulkarni Y.A. (2020). Medicinal Plants from Genus Costus in the Management of Diabetes. In: Phytotherapy in the Management of Diabetes and Hypertension. Volume: 3. Bentham Science Publishers, Singapore. 127-165. DOI: https://doi.org/10.2174/9789811459139120030007

AWARDS/ACHIEVEMENTS

Received "Prof. Manjeeth Singh Award” for presentation of research work related to molecular pharmacology at 52^nd Annual Conference of Indian Pharmacological Society.

1. Listed in "TOP 2% Scientist in the world”. List published by Standford University & Elsevier. 2021 & 2022.
2. Received "Publons Peer Review Awards 2018” for being placed in top 1% of reviewers in the area of "Pharmacology & Toxicology”.
3. Received Best Research Output Award (Year 2015-2016), SVKM’s NMIMS (Deemed to be University), SPP School of Pharmacy & Technology Management, Mumbai.
4. Received travel grant from Science & Engineering Research Board (SERB), Govt. of India for attending conference Pharmacology 2014 organized by British Pharmacological Society, London, UK.
5. Received Best Faculty Award (Year 2012-2013), SVKM’s NMIMS (Deemed to be University), SPP School of Pharmacy & Technology Management, Mumbai.

1. Received INSPIRE Faculty Award 2012 from Department of Science & Technology (DST), Govt. of India.
2. Selected by the American Biographical Institute for Sir Isaac Newton Scientific Award of Excellence For 2012.
3. Admitted as Fellow of Academy of Sciences for Animal Welfare in 2012.

The academy of Sciences for Animal Welfare is working for prevention of cruelty, enhancement of animal health and use of minimum animals for Research & Development. The academy is approved body of Animal Welfare Board which is under Ministry of Environment and Forests, Govt. of India.

1. Listed as Member (Biography) of MARQUIS Who's Who in the World 2012, USA.

11. Received grant from "Department of Science & Technology (DST), of India” under Young Scientist category for attending Experimental Biology 2011 at Washington DC, USA, under "International Travel Support Scheme”.
12. Received travel grant from "All India Council of Technical Education (AICTE)”, New Delhi, India for attending 29th Annual meeting of American College of Toxicology, Tucson, Arizona, USA.