Dr. Mital Patel

Qualification: M.Pharm, Ph.D.

Specialization: Pharmaceutical Quality assurance

E-mail: mital.patel@nmims.edu

Phone: 022-42332000 (Ext- 2027)

Experience: 10 Year (5 year- Academics & 5 Year Research)

Her research interests include Quality Assurance, Impurity profiling, Bioanalysis, Biomarker separation from herbal formulations, LC-MS/MS characterization, and the use of multivariate methods in analytical research. She has supervised research projects by MPharm students and has worked on a Gujcost-funded project. At the Postgraduate level, she has taught various courses as Modern pharmaceutical analysis and Pharmaceutical Regulatory affairs. At the undergraduate level, she has taught various courses related to Pharmaceutical analysis, Instrumental method of Analysis, Pharmaceutical Quality assurance, Pharmaceutical Regulatory science and Good manufacturing practices. Currently, she holds the position of Assistant Professor at SPPSPTM.

Interest areas:

• Quality Assurance and Regulatory affairs
• Quality by design approach
• Impurity Profiling (LC-MS/MS, MS, NMR, FTIR)
• Isolation and Characterization of Compounds
• Multivariate analysis
• Analytical and Bioanalytical method development
• Chemometrics in analytical field
• Experimental design in analytical field
• Biomarker quantification from herbal formulation
• Quantum Dot in Pharmacy
• Metabolomics

Research

• Publications – Total number (International- 19 , National- 1)
• Book Chapters- 3
• Presentations- Total number (International- 8 , National- 6)
• Grant – 1

Ongoing - SVKM’S NMIMS Seed grant – 1,00,000 - Comprehensive chemical degradation behaviour of selected anticancer drug- An Impurity Profiling.

Conferences/Workshops/Seminars attended- 7

Academic activities

She has guided more than six M.Pharm. Students for their research projects and 4 students are currently pursuing under her guidance. Her one student got "Best Thesis Award- Mpharm Quality Assurance”.

Awards

• Received "Certificate of Appreciation” and awarded first prize with 3700 cash in the event for "Innovative Idea challenge”, organized by BNCP and co-hosted by Mumbai university, 28-30 September 2020.
• Recipient of " P. D. Sethi memorial annual award 2017, Certificate of Merit”, Best research paper on application of TLC/HPTLC in pharma, herbal and other chemical analysis.
• Awarded with JRF scholarship during PhD from 2014-2016
• Awarded with SRF scholarship during PhD from 2017-2018
• Merit award and Scholarship from RPCP during MPharm, 2^nd Position in 1st year M. Pharm, CHARUSAT, changa.
• Merit award and Scholarship from RPCP during MPharm, 2^nd Position in 2nd year M. Pharm, CHARUSAT, changa.
• Selected and received offer letter under Government NRHM programme after B.Pharm (on merit basis)

Professional Memberships

• Registered Pharmacist of Gujarat State Pharmacy Council
• Life Member of the Association of Pharmaceutical Teachers of India

Recent Publications

• Nahata Anuj, Patel Mital*, Muchakayal Siva, (2024) Strategic Approaches to Elevate Quality and Sustainability in Drug Development: Comprehensive Pretomanid (PA-824) Chemical Stability study using QbD and Green Chemistry Principles, Microchemical Journal, Vol:200: 110413, Q1, Scopus, IF: 4.8, Cite Score 8.6. https://www.sciencedirect.com/science/article/abs/pii/S0026265X24005253.
• Sandesh Bherje, Mital Patel*, (2024) A green perspective on simultaneous HPLC and UV spectrophotometric estimation of Udenafil and Dapoxetine hydrochloride in pharmaceutical formulations. Green Analytical Chemistry, Scopus https://doi.org/10.1016/j.greeac.2024.100106 .
• Bherje Sandesh, Patel Mital*, A green perspective on simultaneous HPLC and UV spectrophotometric estimation of Udenafil and Dapoxetine hydrochloride in pharmaceutical formulations, Green Analytical Chemistry, 9, 100106. Link: 10.1016/j.greeac.2024.100106.
• Dhas, M. Pastagia, A. Sharma, A. Khera, R. Kudarha, S. Kulkarni, S. Soman, S. Mutalik, R.P. Barnwal, G. Singh, Mital Patel*, Organic quantum dots: An ultrasmall nanoplatform for cancer theranostics, Journal of Controlled Release, 348, (2022), 798-824, ISSN 0168-3659, https://doi.org/10.1016/j.jconrel.2022.06.033. (Impact factor – 11.467)
• Gundecha, S., Patel, M.* & Mayur, Y.C. An Application of Quality by Design and Analytical Greenness Assessment Approach for the Development of Erlotinib Stability Indicating Method. Chromatographia 85, 575–588 (2022). https://doi.org/10.1007/s10337-022-04167-7 . (Impact factor – 2.05)
• Patel M.N., Kothari C.S., An Innovative Impurity profiling of Avanafil using LC and LC-MS/MS with in-silico toxicity prediction, Arabian Journal of Chemistry, ISSN: 1878-5352, (2020), 13(8), 6493-6509. DOI: 10.1016/j.arabjc.2020.06.007, (Impact factor – 5.165).
• Vyas, Darshan, Mital Patel, and Sarika Wairkar. "Strategies for active tumor targeting-an update."European Journal of Pharmacology(2021): 915, 174512. https://doi.org/10.1016/j.ejphar.2021.174512Get. (Impact factor – 432)
• Patel, M.N., Kothari, C.S. A Comprehensive Stability Study of Vardenafil Using Quality by Design Approach.Chromatographia84,751–767 (2021). https://doi.org/10.1007/s10337-021-04059-2. (Impact factor – 02.4)
• Javia A., Bardoliwala D., Patel M.N., Misra A.N., Ligands and Receptors for Targeted Delivery of Nanoparticles: Recent Updates and Challenges, Drug Delivery with Targeted Nanoparticles: In Vitro and In Vivo Evaluation Methods (1st ed.); Jenny Stanford Publishing, (2021), https://doi.org/10.1201/9781003164739.
• Patel M.N., Patel S.G., Patel A.S., Comparative Study of the UV-Chemometrics, Ratio Spectra Derivative and HPLC-QbD Methods for the Estimation of Their Simultaneous Estimation in Combined Marketed Formulation, Chromatographia, ISSN: 0009-5893, 84,75–86 (2021). https://doi.org/10.1007/s10337-020-03979-9 (Impact factor – 024).
• Patel M.N., Kothari C.S., Comprehensive stability-indicating method development of Avanafil Phosphodiesterase type 5 inhibitor using advanced Quality-by-Design approach, Journal of Analytical Science and Technology, ISSN: 2093-3371, (2020), 11(29), 1 – 4, https://doi.org/1186/s40543-020-00228-4 (Impact factor – 2.769).
• Patel M.N., Kothari C.S., Multivariate UV-Chemometric and HPLC-QbD Method for Simultaneous Estimation of Vardenafil and Dapoxetine in Active Pharmaceutical Ingredients and its Marketed Formulation, Current Analytical Chemistry, ISSN: 1573-4110, (2020), 16 (3), 263-276. DOI: 2174/1573411014666180501122512 (Impact factor- 1.365).
• Patel M.N., Kothari C.S., Review on implementation of a multivariate approach for forced degradation study and impurity profiling with regulatory considerations, Chromatographia, ISSN: 0009-5893, (2018), 1, 81, 105-125, DOI: 1007/s10337-017-3393-0 (Impact factor- 1.596).
• Patel M.N., Kothari C. S. Multivariate approaches for simultaneous determination of Avanafil and Dapoxetine by UV chemometrics and HPLC-QbD in binary mixtures and pharmaceutical products, , Journal of AOAC international, ISSN:1060-3271, (2016), 99 (3), 649-663, DOI: 5740/jaoacint.15-0259 (Impact factor - 1.410).
• Ranpariya M, Kothari C, Patel M, Mehta P., Development and validation of a high-performance thin-layer chromatographic—densitometric method for the quantification of guggulsterone E and Z in a polyherbal formulation containing Commiphora Mukul, JPC-Journal of Planar Chromatography-Modern TLC, ISSN: 0933-4173, (2017), 30 (3), 181 -187, DOI: 10.1556/1006.2017.30.3.5, (Impact factor – 815).
• Anuja Jawale, Mital Patel, Charmy Kothari*, Misari Patel, Novel bio-analytical RP-hplc method for simultaneous estimation of aceclofenac and drotaverine hydrochloride in human plasma by doe approach, European Journal of Biomedical and Pharmaceutical Sciences, ISSN 2349-8870.