Dr. Vaishali Londhe

Specialization             : Pharmaceutics

E mail                         : vaishali.londhe@nmims.edu

Phone                         : 022-42332000 (Extn-2030)

Experience                 :  23 years after Ph D (Industry - 9 years, Academics - 14 years)

Industry: Worked in Sun Pharmaceutical Advanced Research Centre as executive and   Aurobindo Pharmaceutical Limited Research Centre, Mumbai as Group leader responsible for analytical method development, validation, documentation etc.

Academics:

• PG Chairperson from 1^st July 2022 – 30^th June 2023
• Section Head Pharmaceutics from 1^st July 2021 –30^th June 2022
• Head of Pharmaceutics and allied Departments from July 2020 -30^th June 2021
• Head Of Department - Quality Assurance from July 2009 – September 2012 and 28^th March 2013 till 30^th April 2015
• In-charge Head of Department for Pharmaceutics from February 2010 – June 2010
• Head of Department of Industrial Pharmacy from 1^st September 2016 – 30^th November 2017
• Chairperson for Part time M Pharm since February 2011 – 2013
• In-charge Project Placement Committee since February 2011 -2015
• In-charge Central Instrumentation Laboratory, SPPSPTM since June 2015 – April 2017, December 2017 – 30^th June 2021
• Extracurricular Committee In-charge from May 2017 – 1^st December 2017

Interest areas:

• Novel drug delivery systems like nanoparticles, liposomes, microneedles
• Solubility enhancement methods like solid dispersions, inclusion complexation, SMEDDS, co-crystals for improvement in bioavailability
• Modified oral delivery like ODT, oral jelly etc. using Design of Experiments (DOE)
• Transdermal drug delivery
• Analytical/ bioanalytical method development and validation, impurity profiling
• Herbal formulation development

Research

• Publications – Total number (International-67, National-5)
• Books- Nil
• Book Chapters- 4
• Patents- 4 (Granted) + 1published + 1 provisional
• Presentations- Total number (International- 17, National-23)
• Government funded projects – Total number 1        

• Completed (‘Microneedles: can be a good option for antipsychotic drug delivery?’ , DST SERB, Rs 3083360)

• Ongoing (Nil)

• Industry projects
  • Completed (4)

1. Analytical Method development and validation for Assay and related substances of Isotretinoin liposomal gel by IPCA Laboratories Ltd – Rs. 1.5 Lakh (completed)
2. Dermatopharmacokinetic studies of Derma Products by Ajanta Pharma Ltd – Rs 47,200 (Completed)
3. Formulation and evaluation capsules containing solubilized Febuxostat for bioavailability enhancement – Rs. 25,000 by ACG Capsules (Completed)
4. To Prepare orally disintegrating film of Sildenafil using pullulan – Rs 1,00,000/- by Nagasse India Pvt Ltd (Completed)

• Ongoing (1)

Systematic investigation and screening of super refined excipients (SR excipients) relevant as Penetration enhancer (PE’s) / solubilizers in adhesive based transdermal patch formulations’ – by Croda India Company Pvt Ltd, Total amount Rs 2,84,970, Started in September 2022

Conferences/Workshops/Seminars attended-  15

Academic activities

She has guided 110 M.Pharm. Students for their research projects.

She has guided 6 PhDs successfully and 4 candidates are registered under her supervision. 

 Awards

• DST International Travel Scheme (ITS) of Rs 62700/- to attend and to participate in "46th Controlled Release Society Annual meeting and Exposition, Spain (21 July, 2019 to 24 July, 2019)
• DST Travel grant (Rs 92,036/-) and NMIMS grant (Rs 50,000/-) to present posters at AAPS 2012 Annual Conference and Exhibition held on 14-18th October 2012 at Chicago IL

Professional Memberships

• Registered Pharmacist (Life member) under Maharashtra State Pharmacy Council.
• Life member of Indian Pharmaceutical Association
• Member of Controlled Release Society, Local Chapter
• Life member of Association of Pharmaceutical Teachers of India
• Life member of Society of Pharmaceutical Education and Research (SPER)

Recent Publications

1. Jalundhwala, F. and Londhe, V. (2023), "A systematic review on implementing operational excellence as a strategy to ensure regulatory compliance: a roadmap for Indian pharmaceutical industry", International Journal of Lean Six Sigma, Vol. 14 No. 4, pp. 730-758. https://doi.org/10.1108/IJLSS-04-2022-0078, (Impact factor – 5.686)
2. Vaishali Y Londhe, Rupali S Bhadale, Zein-maltodextrin nanocomplex based dissolving microneedle: A promising approach for Paliperidone palmitate delivery, International Journal of Biological Macromolecules, Volume 244, 31 July 2023, 125418
3. Forum Jalundhwala, Vaishali Londhe, Bharat Shah, Ensuring regulatory compliance by quality by design (QbD) approach to optimize the manufacturing process of API: ferric ammonium citrate as an example, Chemical Papers, volume 77, pages 1469–1477,  March 2023
4. Rupali S. Bhadale, Vaishali Y. Londhe, A comparison of dissolving microneedles and transdermal film with solid microneedles for iloperidone in vivo: a proof of concept’ in the Naunyn-Schmiedeberg's Archives of Pharmacology  2023 Feb;396(2):239-246. (Impact Factor 3.195)
5. Rupali Bhadale, Vaishali Londhe, Solid microneedles assisted transepidermal delivery of iloperidone loaded film: Characterization and skin deposition studies, Journal of Drug Delivery Science and Technology, 79 (2023) 104028