Dr. Kavita Singh

Qualification              : M.Pharm., Ph.D.(Tech.), PGDPL.

Specialization            : Pharmaceutics

E mail                         : kavita.singh@nmims.edu

Phone                         : 022-42332000 (Extn- 2092)

Experience                : 10.5 years (Industry: 2 years, Academics: 8.5 years)

She has 2 years’ work experience in industries like Pfizer India Pvt. Ltd. and Ipca Labs Pvt. Ltd as Research Associate. She has worked as Senior Research Fellow for research project sponsored by Relmada Therapeutics, USA during doctoral research. 

Interest areas:

Expertise in development of various formulations viz. Polymeric and lipid based Nano carriers, Novel ophthalmic drug delivery systems, Osmotic drug delivery systems, Colon targeted and extended release matrix based oral solid dosage forms, anti-aging interventions, Pharmacokinetic studies etc. She carries keen interest in exploring novel anti-aging modalities and is engaged in multiple industrial projects in this arena. 

Research

• Publications – 23 (International- 18, National- 05 )
• Book Chapters- 05
• Patents- 3 ( 01 granted, 02 Filed)
• Presentations- 25 (International- 09, National-  16 )
• Government funded projects – 02
  • Completed (02)
  • Ongoing (01)
  • Received Research grant of approx. 30 Lacs under the scheme, Core Research Grant of Science & Engineering Research Board (SERB), DST, Govt. of India for the project entitled "Development of Novel formulation for minimally invasive or non-invasive ocular delivery of Anti-VEGF macromolecule for retinoblastoma” from March 2021-2024.
  • Received Research grant of approx. 41 Lacs under the scheme, Early Career Research Award of Science & Engineering Research Board (SERB), DST, Govt. of India for the project entitled "Development and assessment of novel formulations containing therapeutic proteins and siRNA for treatment of Diabetic retinopathy” from March 2018-2021.

• Polymeric Nanoparticulate systems have been developed for an antiglaucoma agent to prolong the release of drug to the Ocular Membrane funded by University of Mumbai. (Rs. 22,000) from July 2007-June 2008.

• Industry projects

• In-vivo pharmacokinetic evaluation of a topical formulation; funded by Vici Health Sciences, USA. (Approx. Rs. 20 lacs) from May 2022 to April 2023.
• Development of ophthalmic suspension to cure ocular inflammation; funded by Vici Health Sciences, USA. (Approx. Rs. 17 lacs) from Oct 2021 to Dec 2022.
• Evaluation of anti-aging potential of novel Elixir formulation; funded by Nugenics Research Pvt Ltd, Mumbai, India. (Approx. Rs. 10 lacs) from Jan-Dec 2022.
• Evaluation of anti-aging potential of novel Elixir formulation; funded by Nugenics Research Pvt Ltd, Mumbai, India. (Approx. Rs. 10 lacs) from Jan 2021 to Dec 2021.
• Development of novel Anti-aging modalities; funded by Nugenics Research Pvt Ltd, Mumbai, India. (Approx. Rs. 25 lacs) from Nov 2017 to Dec 2020.
• In-vivo Pharmacokinetic Evaluation of lipidic Formulations; funded by Gattefosse India Pvt. Ltd., Mumbai, India. (Approx. Rs. 4.72 lacs) from Oct 2019 to Sep 2020.
• Pharmacokinetic Evaluation of Curcumin Formulation with Gelucire 48/16; funded by Gattefosse India Pvt. Ltd., Mumbai, India. (Approx. Rs. 5 lacs) from Feb 218 to Aug 2018.
•  "iDisso setup and visual monitoring studies” & "Statistical Assessment of Drug Release Profiles and Analysis of Dissolution Aliquots Subjected to Varied Dilution and Mixing Efficiency” for ELECTROLAB, Mumbai.
• "Evaluation of Dermatological Products: Ex-vivo diffusion and permeation studies through human cadaver skin”, for CLAIMS Pvt Ltd, Mumbai.
• "Herbal formulation development” for Vedic Life Sciences, Mumbai. 

Conferences/Workshops/Seminars attended- More than 25 

Academic activities

• She has guided 19 M.Pharm. students for their research projects.
• She has 03 Ph.D. scholars and 01 Junior research fellow registered under her supervision working on Government and Industry funded research projects. 
• Kavita Singh is appointed as Technical Expert for E-content and video development for Units of Physical Pharmacy under National mission on education through information and communication (NMEICT), Consortium for Educational Communication, UGC MHRD PROJECT by Educational Multimedia Research Centre (EMMRC) as per the guidelines framed by UGC, Consortium for Educational Communication.
• Appointed as External referee for conducting Viva-Voce examinations of B. Pharm and M. Pharm. (Pharmaceutics) students from University of Mumbai and SNDT Women’s University. 

 Awards

• PhD student at SPPSPTM, Ms. Shibani Supe under the guidance of Kavita Singh received BEST POSTER award for her work entitled "Optimized polyethylenimine (PEI) based lipopolyplexes for siRNA delivery, analyzed in vitro for targeting VEGF indirectly” at 6th Annual International Conference on Global Trends in IPR:Patenting and Beyond, organized by Goa – Center for Excellence in Intellectual Property [G-CEIP] held in Dec 2021. The work presented in the conference was outcome of a government funded (approx. INR 42 Lacs) research project under the scheme of Early Career Award, SERB DST, GOI received by Dr. Kavita Singh in capacity of Principal Investigator.
• Kavita Singh from SPP-SPTM NMIMS, University, Mumbai along with Team Gattefossé India participated in an event Disso Research Presentations India-2021 (DRPI 2021) and presented a research work entitled "In-vitro Dissolution Vs In-vitro Lipolysis: Which is better to predict the In-vivo performance of Lipid Formulations?”.

• Received international travel support of Rs. 2 lacs to present research work entitled - Development and Evaluation of Hydrogel Based Contact Lens of Ganciclovir for Treatment of Cytomegalovirus Retinitis, at 2017 AAPS Annual Meeting and Exposition, held in San Diego, USA from 12-11-2017 to 15-11-2017.
• Received 3rd prize for oral presentation on project entitled "Formulation and development of gabapentin–loaded lipid nanoparticle gel” in a conference on Novel Formulation Strategies, held on 12-13 April 2018 at Ramada Powai Hotel and Convention Centre, Mumbai, India.
• Received Early Career Research Award of Science & Engineering Research Board (SERB), DST, Govt. of India Research grant of approx.. Rs. 41 Lakhs, for the project entitled "Development and assessment of novel formulations containing therapeutic proteins and siRNA for treatment of Diabetic retinopathy.” 
• Obtained 4th rank in P.G. Diploma in Patent Law from NALSAR University of Law, Hyderabad, India in May 2017 with A+ grade.
• First Prize for poster presentation entitled "Investigation of In-vitro In vivo release profiles of Buprenorphine HCl loaded nanoparticles for colon targeting” at DISSO INDIA 2013, International Annual Symposium organized by Society of Pharmaceutical Dissolution Science at Mumbai, India.
• Awarded Senior Research Fellowship for the doctoral research by Council of Scientific and Industrial Research, Govt. of India, New Delhi, India in April 2012.
• Ratan Tata scholarship, Sir Dorabji Tata Trust, Fort, Mumbai for the Year 2001-2002.

Professional Memberships

• Life member of Indian Pharmaceutical Association 
• Life member of Association of Pharmaceutical Teachers of India

Recent Publications

1. Shibani Supe, Archana Upadhya, Santosh Tripathi, Vikas Dighe, Kavita Singh. Liposome polyethylenimine complexes for the effective delivery of HuR siRNA in the treatment of diabetic retinopathy. Drug delivery and translational research. 2023 Jun;13(6):1675-1698.
2. Mudassir Ansari, Yogesh A Kulkarni, Kavita Singh. Advanced technologies of drug delivery to the posterior eye segment targeting angiogenesis and ocular cancer. Critical Reviews in Therapeutic Drug Carrier Systems. 2023 January; DOI: 10.1615/CritRevTherDrugCarrierSyst.2023045298. Online ahead of print.
3. Mohit Harsolekar, Mudassir Ansari, Shibani Supe, Kavita Singh. Formulation development and evaluation of therapeutic contact lens loaded with ganciclovir. International Ophthalmology. 2023 43, pages 2225–2236.
4. Shreyashi Mazumdar, Bala Prabhakar, Shraddha Khairnar, Kavita Singh. Mucoadhesive film of liquorice and chlorhexidine gluconate for treating mouth ulcers. Indian Journal of Pharmaceutical Education and Research. May 2023; 57(2s):s274-s280.
5. Shraddha I Khairnar, Yogesh A Kulkarni, Kavita Singh. Cardiotoxicity linked to anticancer agents and cardioprotective strategy. Archives of Pharmacal Research. 2022 October; 45(10): 704-730.
6. Shibani Supe, Archana Upadhya and Kavita Singh. Role of small interfering RNA (siRNA) in targeting ocular neovascularization: A review. Experimental Eye Research. 2021 January; 202; 108329.
7. Ujwala Shinde, Prajakta Joshi, Divya Jain & Kavita Singh. Preparation and Evaluation of N-Trimethyl Chitosan Nanoparticles of Flurbiprofen for Ocular Delivery. Current Eye Research. 2019 May; 44(5):575-582.
8. Ujwala Shinde, Sheela Modani and Kavita Singh. Design and Development of Repaglinide Microemulsion Gel for Transdermal Delivery. AAPS PharmSciTech. 2018 Jan; 19(1):315-325.
9. Kavita Singh *, Amrita Bajaj, Aditya Marfatia, Manish Gupta, Agnivesh Shrivastava. Study of drug release profiles obtained by auto-dilution and auto-mixing of dissolution aliquots of Naproxen Sodium tablets IP: A Statistical Evaluation. Asian Journal of Pharmaceutics. Oct-Dec 2016 suppl / 179.
10. Anjali Kudtarkar, Ujwala Shinde, Gopal Bharkad and Kavita Singh. Solid lipid nanoparticles of albendazole for treatment of toxocara canis infection: in-vivo efficacy studies. Nanoscience & Nanotechnology-Asia, 2016; 6(3):1-12.