Dr. Kunal Mohan Gokhale

Qualification : Ph.D.(Tech)  

Specialization : Pharmaceutical Chemistry

E mail : kunal.gokhale@nmims.edu

Phone: 022-42332000 (Extn-2029)

Experience: 16 yrs. (Academic)

He has 16 years’ experience with Dr. L. H. Hiranandani College of Pharmacy, Ulhasnagar, in teaching undergraduates and postgraduate subjects like Medicinal Chemistry, Pharmaceutical Organic Chemistry, Green Chemistry and Catalysis, Process Chemistry. He completed his B. Pharm from Prin. KMK College of Pharmacy, Mumbai in 2004; M. Pharm in Medicinal Chemistry from MUICT (then UDCT) in 2006, where his topic for research was synthesis of ferulic acid derivative and its anticancer evaluation. He pursued his Ph. D (Tech) in Pharmaceutical Chemistry from ICT, Mumbai in 2021. His Ph. D work was related to Synthesis and anti-Tb evaluation of novel peptidomimetic PDF inhibitors.

Interest areas:

• Green Chemistry and Process Development
• Synthesis and derrivatization of compounds of natural origin like curcumin, isoflavones, flavanones, thiazolidinones,
• Anticancer and Anti-Tb evaluation of NCE’s
• Development of M@ZIF (Metal incorporated zeolitic imidazolic framework)

Research

• Publications – International- 10, National-7
• Book Chapters- 1
• Patents- 1
• Presentations- International- 4, National-  4       
• Government funded projects – 6
  • Completed
• Development of suitable formulation for hydrophobic drug using natural polymer derivative, funded by University of Mumbai, Rs. 60,000/-
• Chemical Synthesis and biological evaluation of phytochemicals (Flavanones), Funded by University of Mumbai, Rs. 20,000/-
• Pharmacological Evaluation of Lagenaria siceria fruit juice on alcohol induced liver damage, funded by University of Mumbai, Rs. 30,000/-
• Pharmacological evaluation of lipid lowering activity of fruit of Careya arbora, funded by University of Mumbai, Rs. 15,000/-
• Synthesis of ranitidine and development of suitable formulation for single oral use, funded by University of Mumbai, Rs. 25,000/-
• Prebiotic and pharmacological evaluation of FOS, funded by Bhavan’s College, Andheri, Rs. 73,000/-
• Industry projects

Completed

• Pathogenicity study of nattokinase producing enzymes in mice funded by Viridis Biopharma, Rs. 22,000/- (as Co-PI)
• Oral repeated dose 28 days’ toxicity study on nattogold in mice, funded by Viridis biopharma, Rs. 22,000/- (as Co-PI)

Conferences/Workshops/Seminars attended- 20 

Academic activities

He has guided 13 M. Pharm. students for their research projects. 

Professional Memberships

• Indian Pharmaceutical Association
• Association of Pharmaceutical Teachers of India

Recent Publications

1. Kunal M. Gokhale, Darshika Parmar, Urmila J. Joshi, Khushboo Begwani, Novel substituted 5 arylidene-1, 3-thiazolidin-4-one analogues: Synthesis, optimization, anticancer screening and docking studies, J. Pharm. Neg. Results, 2022, 13 (06),2378-2389.
2. Kunal M. Gokhale, Aditya Iyer, Deployment of iron uptake machineries as targets against drug resistant strains of Mycobacterium tuberculosis, Ind. J. Pharmacol, 2022, Sep-Oct, 54(5), 353-363.
3. Kunal M. Gokhale, Dhara S. Pandey, Formulation development of novel curcumin analogue loaded non-aqueous gel and curcumin loaded nanoparticle (CA-NP) gel for topical use and In-vitro antioxidant study, J. Pharm Res. International., 2021, 33 (58B), 284-302.
4. Kunal M. Gokhale, Sanmita G Lotlikar, Boron based synthesis of curcumin analogues and their In-Vitro antioxidant and anticancer evaluation, J. Oriental. Res., 2021, XCII-V, 415-426.
5. Kunal M. Gokhale, Vikas N. Telvekar, Novel peptidomimetic peptide deformylase (PDF) inhibitors of Mycobacterium tuberculosis, Chem. Bio. Drug. Des., 2021, 97 (1), 148-156.