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RESEARCH (2009-2010)

Publications (2009-2010)

• Kaur G, Chintamaneni M, Addepalli V, Agrawal SS. Evaluation of Hepatoprotective activity of Ocimum sanctum in HepG2 Cell Line. Archives of Pharmaceutical Sciences and Research. July 2009, 1(1):25-30. 

• Yele SU, Addepalli V. Toxicological assessments of aqueous extract of Eugenia jambolana stem bark. Pharmaceutical Biology. July 2009, 48(8):849-854. 

• Prabhakar B, Rane S. Influence of Liposome Composition on Paclitaxel Entrapment and pH Sensitivity of Liposomes. International Journal of PharmTech Research. July-September 2009, 1(3):914-917. 

• Kulkarni YA, Addepalli V. Toxicological screening of methanolic extract of Gmelina arborea in experimental animals. Planta Medica. August 2009, 997. 

• Pathak G, Addepalli V. Effect of Traditional Ayurvedic Arjuna Formulations on Cardiometabolic Disorders. Planta Medica. August 2009, 1008. 

• Yele SU, Addepalli V. Antihyperglycemic activity of aqueous stem bark extract of Eugenia jambolana in alloxanized rats. Planta Medica. August 2009, 1010. 

• Sateesh B, Addepalli V. Restoration of altered homeostasis in type 2 diabetic animals by an Ayurvedic Formulation. Planta Medica. August 2009, 1011. 

• Mehta A, Tuli R, Chintamaneni M, Kaur G. Antioxidants: The Need of Hour. Pharmacologyonline. August 2009, 2:650-661. 

• Kaur G, Tuli R, Chintamaneni M. Antioxidant Potential of Methanolic and hydrolyzed Extracts of Eclipta alba. Pharmacologyonline. August 2009, 2:947-956. 

• Nerkar AG, Ghone SA, Thaker AK. In Silico Screening and ADME Predictions of Some Quinazolinones as Potential Dihydrofolate Reductase Inhibitors for Anticancer Activity. Asian Journal of Chemistry. August 2009, 21(7):5363-5372. 

• Gavali DK, Kulkarni KS, Kumar A, Chakraborty BS. Therapeutic class - specific signal detection of bradycardia associated with propranolol hydrochloride. Indian Journal of Pharmacology. August 2009, 41(4):162-166. 

• Kaur G, Chintamaneni M. Antinociceptive Effects of Combinatorial Extract of Curcumin - Integration of Traditional and Modern Concepts. The Journal of Clinical Pharmacology. September 2009, 4(9):1109. 

• Bhatt LK, Addepalli V. Enhanced MMP-2 and MMP-9 inhibition: An approach to treat diabetic nephropathy. The Journal of Clinical Pharmacology. September 2009, 4(9):1111. 

• Bhatt LK, Addepalli V, Acharya R. Protective Effect of Ethical Acetate extract of Black Tea in Cardiovascular Complication of Diabetes. The Journal of Clinical Pharmacology. September 2009, 4(9):1111. 

• Sharma G, Addepalli V, Chintamaneni M, Majumdar D. Effect of comorbid conditions on prescription pattern and over all treatment cost of hypertensive patients: A Pharmacoeconomic perspective. The Journal of Clinical Pharmacology. September 2009, 4(9):1111. 

• Addepalli V, Sateesh B, Jayavant MJ. Diabetes Awareness Programme: recruitment methods and results. The Journal of Clinical Pharmacology. September 2009, 4(9):1112. 

• Sateesh B, Addepalli V. Restoration of altered homeostasis in diabetic animals by (Morsina) Ayurvedic Formulation. The Journal of Clinical Pharmacology. September 2009, 4(9):1112. 

• Roy S, Pal K, Anis A, Pramanik K, Prabhakar B. Polymers in Mucoadhesive Drug-Delivery Systems: A Brief Note. Designed Monomers and Polymers. October 2009, 12(6):483-495. 

• Baheti S, Saraswathy N, Kulkarni KS. Evaluation of Effects of Black Tea and Coffee on Learning Process and Memory in Healthy Human Volunteers. International Journal of Pharmaceutical and Clinical Research. October-December 2009, 1(3):119-123. 

• Das S, Deshmukh R. Advances in Vaccination: A Review. International Journal of Applied Pharmaceutics. November 2009, 1(1):1-21. 

• Belemkar S, Addepalli V. Antidiabetic Ayurvedic formulation (Limit) attenuate progression of Kidney damage in streptozotocin-nicotinamide induced diabetic rats. American Association of Pharmaceutical Scientists Journal. November 2009, 11(S2): Abstract 004077. 

• Addepalli V, Belemkar S, Jain JM. Evaluation of Safety and Efficacy of Limit, An Ayurvedic Formulation: A Double Blind, Placebo Controlled Study in Type 2 Diabetic Patients with Secondary Failure to Oral Hypoglycemic Agents. American Association of Pharmaceutical Scientists Journal. November 2009, 11(S2): Abstract 003115. 

• Kumar P, Saraswathy N, Kulkarni K. Evaluation of Effect of Green Tea and Saffron on Learning Process and Memory in Healthy Human Volunteers. Pharmacologyonline. November 2009, 2:782-796.

• Pradhan V, Gaikwad R, Samad A, Prabhakar B. Formulation and Evaluation of Almotriptan Malate Nasal Drops. Indian Journal of Pharmaceutical Sciences. November-December 2009, 71(6):727-729. 

• Nerkar AG, Ghone SA, Thaker AK. In Silico Screening and ADME Predictions of 6, 6'-Methylene-BIS-2-Methyl-3-((2'-Aryl)-Imidazolidin-4'-one) Quinazolin-4(3H)-one derivatives as potential DHFR as Potential DHFR inhibitors for anticancer activity Part-I. International Journal of Chemical Science. December 2009, 7(2):1205-1217. 

• Gupta A, Gaud RS, Srinivasan G. Development, evaluation and optimization of extended release buccal tablets prepared using progressive hydration technology. International Journal of Drug Delivery. January 2010, 37-48. 

• Yele SU, Gokhale SB, Surana SJ, Addepalli V. Diuretic and Laxative Activity of Cassia sophera Linn, a Prevalent Western Ghat Species. Pharmacologyonline. January 2010, 1:47-52. 

• Gupta A, Gaud RS, Srinivasan G. Development of Discriminating Dissolution Method for an Insoluble Drug Nisoldipine. International Journal of PharmTech Research. January-March 2010, 2(1):931-939. 

• Sherje AP, Tawade AP, Vyas M. Simultaneous Spectrophothometric Determination of Satranidazole and Ofloxacin in Combined Dosage Form. International Journal of PharmTech Research. January-March 2010, 2(1):511-514. 

• Shinde TT, Chintamaneni M, Bhut VG, Raval DK. DIC: Awareness. Deccan Journal of Pharmaceutics and Cosmetology. January-March 2010, 1(1):59-62. 

• Gupta H, Kumar S, Roy SK, Gaud RS. Patent protection strategies. Journal of Pharmacy & Bioallied Sciences. January-March 2010, 2(1):2-7. 

• Kaur G, Chintamaneni M. Antisense Therapy for Cancer - Present and Future Prospects. Pharma Times. January 2010, 42(1). 

• Prabhakar B, Roy S. Bioadhesive Polymeric Platforms for Transmucosal Drug Delivery Systems - A Review. Tropical Journal of Pharmaceutical Research. February 2010, 9(1):91-104. 

• Kadu PK, Sangave P. Enzymatic method for the synthesis of glyceryl monosterate. Journal of Pharmacy research. February 2010, 3(2):386-387. 

• Bhatt LK, Addepalli V. Attenuation of diabetic retinopathy by enhanced inhibition of MMP-2 and MMP-9 using aspirin and minocycline in streptozotocin-diabetic rats. American Journal of Translational Research. February 2010, 2(2):181-189. 

• Bhatt LK, Bansal J, Piplani P, Bondhankar SL, Addepalli V. Cardioprotective and β-adrenoceptor antagonistic activity of a newly synthesized aryloxypropanolamine derivative PP-36. Journal of Experimental Pharmacology. February 2010, 2:37-45. 

• Nandave M, Parthasarathy S, Sai-Sudhakar CB. Circulating Thrombus Causes Release of Endothelial Cells and Endothelial Cells Derived Particles. Journal of Surgical Research. February 2010, 158(2):362-363. 

• Prabhavalkar KS, Chintamaneni M. Diagnosis and treatment of mild cognitive impairment: A review. Journal of Pharmacy research. February 2010, 3(2):388-392. 

• Prabhavalkar KS, Chintamaneni M. Safety and Efficacy of Herbal Formulation for Nootropic Activity. International Journal of Pharma Research and Development. March 2010. 

• Bhatt LK, Addepalli V. Minocycline with aspirin: a therapeutic approach in the treatment of diabetic neuropathy. Neurological Sciences. March 2010, 31(6):705-716. 

• Gupta A, Gaud RS, Srinivasan G. Development of Buccal adhesive formulations using in- situ formation of interpolymer complex and optimization using Box-Benhken design. International Journal of Advances in Pharmaceutical Sciences. March 2010, 1(1):86-95. 

• Das S, Suresh PK, Deshmukh R. Design of Eudragit RL 100 nanoparticles by nanoprecipitation method for ocular drug delivery. Nanomedicine: Nanotechnology, Biology, and Medicine. April 2010, 6(2):318-323. 

• Sawant L, Pandita N, Prabhakar B. Determination of gallic acid in Phyllanthus emblica Linn. dried fruit powder by HPTLC. Journal of Pharmacy & Bioallied Sciences. April-June 2010, 2(2):105-108. 

• Roy SK, Prabhakar BR. Design and characterization of Acrylate based Buccoadhesive tablets of Diltiazem hydrochloride. International Journal of ChemTech Research. April-June 2010, 2(2):965-972. 

• Joshi H, Gururaja MP, Suares D. Calotropis gigantea R. Br. (Asclepiadaceae): A Review. International Journal of Pharmaceutical Research. May 2010, 3(1):10-14. 

• Jain S, Kaur G, Jain VK. Intellectual Property and Intellectual Property Rights. Journal of Pharmaceutical Sciences and Research. May 2010, 2(5):314-316. 

• Shah D, Gaud RS, Misra AN, Parikh R. Formulation of a Water Soluble Mucoadhesive Film of Lycopene for Treatment of Leukoplakia. International Journal of Pharmaceutical Sciences Review and Research. May-June 2010, 2(1):6-10.

• Pawar AS, Barve K. Novel Approaches to the Therapy of Depression. Pharmacology online. May-August 2010, 2:850-857. 

• Barve K, Laddha KS, Jayakumar B. Use of enzyme to facilitate extraction of safed musli. Indian Drugs. May 2010, 47(5):46-47.

Paper Presentations (2009-2010)

• Das S, Gupta A (August 2009), Nanoparticles as a Potential Drug Delivery System for the Ocular Surface: Characterization, stability studies presented at Nanotech India - 2009, Kerala. 

• Bhatt LK, Addepalli A, Kaur G (September 2009), Enhanced MMP-2 and MMP-9 Inhibition: An approach to treat Diabetic Nephropathy presented at 38th ACCP Annual Meeting, San Antonio, Texas, USA. 

• Kaur G, Chintamaneni M (September 2009), Antinociceptive effects of Combinatorial Extract of Curcumin - Integration of Traditional and Modern Concepts presented at 38th ACCP Annual Meeting, San Antonio, Texas, USA. 

• Sateesh B, Addepalli V, Kaur G (September 2009), Restoration of Altered Homeostasis in Diabetic Animals by Mersina Ayurvedic Formulation presented at 38th ACCP Annual Meeting, San Antonio, Texas, USA. 

• Pradhan V (September 2009), Formulation and evaluation of Almotriptan malate nasal drops presented at Conference on Nasal & Pulmonary Drug Delivery, Mumbai, Maharashtra. 

• Kaur G, Chintamaneni M (October 2009), Antihyperlipidemic potential of combinatorial extract of curcumin in triton-induced byperlipidemia in rats presented at Third International Annual Conference on Drug Discovery & Development - Challenges in Partnership, Mumbai, Maharashtra. 

• Barve KH, Patel JM (October 2009), Intestinal Permeability of Lamivudine using Single Pass Intestinal Perfusion (SPIP) presented at Third International Annual Conference on Drug Discovery & Development - Challenges in Partnership, Mumbai, Maharashtra. 

• Bhandary S (October 2009), In-vitro and ex-vivo evaluations of a novel Gastro-Intestinal Mucoadhesive Patch System containing Drug X for oral drug delivery presented at Third International Annual Conference on Drug Discovery & Development - Challenges in Partnership, Mumbai, Maharashtra.

• Sherje AP (October 2009), Spectrophothometric Quantitation of Nitazoxanide and Ofloxacin in Combined Dosage Form presented at 14th National Convention of APTI, Jodhpur, Rajasthan. 

• Addepalli V, Belemkar S, Jain J (November 2009), Evaluation of Safety and Efficacy of Limit, An Ayurvedic Formulation: A double blind placebo controlled study in type 2 diabetic patients with secondary failure to Oral Hypoglycemic agents presented at 2009 AAPS Annual Meeting and Exposition, Los Angeles, CA, USA. 

• Belemkar S, Addepalli V (November 2009), Antidiabetic Ayurvedic Formulation (Limit) attenuate progression of kidney damage in Streptozotocin-Nicotinamide induced Diabetic rats presented at 2009 AAPS Annual Meeting and Exposition, Los Angeles, CA, USA. 

• Bhatt LK, Ingle D, Jai S, Addepalli V (December 2009), Attenuation of diabetic nephropathy by ethyl acetate extract of Black Tea in streptozotocin-diabetic rats presented at 61st Indian Pharmaceutical Congress, Ahmedabad, Gujarat.

• Kaduskar D, Prabhakar B (December 2009), Time controlled rupturable press coated single pulse delivery system for rheumatoid arthritis presented at 61st Indian Pharmaceutical Congress, Ahmedabad, Gujarat. 

• Roy SK, Prabhakar B (December 2009), Formulation of Bioerodible immediate release Buccal Tablet using HPMC Acrylate Polymers presented at 61st Indian Pharmaceutical Congress, Ahmedabad, Gujarat. 

• Sawant L, Pandita N (December 2009), Development and validation of HPTLC densitometric quantification method for Gallic acid from Phyllanthus emblica Linn presented at 61st Indian Pharmaceutical Congress, Ahmedabad, Gujarat. 

• Nerkar AG, Ghone SA, Thaker AK (December 2009), In Silico Design, Synthesis and Evaluation of Pyridine Carbohydrazide Schiff’s Bases as Dihydofolate Reductase Inhibitors for Anticancer Activity presented at 61st Indian Pharmaceutical Congress, Ahmedabad, Gujarat. 

• Patel HP, Desai CT, Thaker AK (December 2009), Statistical Process Control to Weight Variation of Solid Dosage Forms presented at 61st Indian Pharmaceutical Congress, Ahmedabad, Gujarat. 

• Sherje AP, Rahigude A, Chokshi J, Vanshiv SD (December 2009), Quantitative spectrophotometric estimation of Nitazoxanide using hydrotropic solubilization technique presented at 61st Indian Pharmaceutical Congress, Ahmedabad, Gujarat. 

• Chintamaneni M, Bhut VP, Shinde TT, Raval DK (December 2009), DIC: Awareness presented at 61st Indian Pharmaceutical Congress, Ahmedabad, Gujarat. 

• Desai V, Desai S, Thomas R, Mazumder A (December 2009), A Study of Knowledge and Attitudes of Community Pharmacists towards Pharmacovigilance and Adverse Drug Reactions in Gujarat presented at 61st Indian Pharmaceutical Congress, Ahmedabad, Gujarat. 

• Ladhe D, Sangave P, Mazumder A, Tewary U (December 2009), Study and Evaluation of Medication Errors in Multispecialty Hospital in Mumbai presented at 61st Indian Pharmaceutical Congress, Ahmedabad, Gujarat. 

• Desai S, Desai V, Thomas R, Mazumder A (December 2009), Evaluation of the usage of Ondansetron in Pediatric Population presented at 61st Indian Pharmaceutical Congress, Ahmedabad, Gujarat. 

• Pathak G, Addepalli V (January 2010), 3H-Hyperlidemia, Hypertension and Heart: Ayurveda as an Adjuvant presented at International Conference on Integrated Holistic Healing, Nagpur, Maharashtra. 

• Medhane D, Ghone S, Mohanraj K, Addepalli V (January 2010), Design and Synthesis of Chalcone Analogues as VEGFR-2 Inhibitors for Tumor Anti-Angiogenesis Activity presented at 14th International Conference on Chemical Biology for Discovery; Perspectives and Challenges, Lucknow, Uttar Pradesh. 

• Gupta A, Gaud RS, Srinivasan G (January 2010), Development and Optimization of Nisoldipine Buccal Tablets presented at 2010 Singapore symposium on Drug Delivery System, Singapore. 

• Bhandary S (February 2010), Oral drug delivery using gastro-intestinal mucoadhesive patch system (GIMAPS) presented at 1st AAPS - NUS - BCP regional conference, Pharm Sci@India 2010, Mumbai, Maharashtra. 

• Kaur G, Chintamaneni M (February 2010), Amelioration of obesity and glucose intolerance in high-fat diet and low-dose streptozotocin induced diabetic rats by combinatorial extract of curcumin presented at 1st AAPS-NUS-BCP Regional Conference PharmSci@India10 on Research The Young Scientist, Mumbai, Maharashtra. 

• Bhandary S (March 2010), Formulation and evaluation of GIMAPS for oral drug delivery presented at Drug discovery Technology World Asia 2010, Singapore. 

• Gatne D, Addepalli V, Ghone S, Mohanraj K (March 2010), Design and synthesis of VEGFR-2 ligands as tumor angiogenesis inhibitor presented at Frontiers in Medicinal Chemistry, Münster, Germany. 

• Sangave P, Sawant L, Pandita N, Kachwala Y, Dhanashree M (March 2010), Screening of antioxidant activity of different solvent extracts of Cassia absus presented at National Symposium on Antioxidants: Current trend in research, Maharashtra. 

• Kadu PK, Sangave P (March 2010), Enzymatic Esterification of Racemic Flurbiprofen presented at International Seminar on Recent Developments in Pharmacological Research, Pune, Maharashtra. 

• Pandey H, Mantri M, Pandita N (March 2010), Antioxidant activity of Butea frondosa presented at International Seminar on Recent Developments in Pharmacological Research, Pune, Maharashtra.

• Narkhede SS (March 2010), Design, synthesis of novel molecules as Anti-infective agents presented at Drug Discovery for Infectious Diseases, Mumbai, Maharashtra. 

• Bhatt LK, Addepalli V (April 2010), Potentiation of aspirin induced cardioprotection by minocycline against myocardial ischemia reperfusion injury in streptozotocin diabetic rat presented at Experimental Biology 2010, Anaheim, CA USA. 

• Kulkarni YA, Addepalli V (April 2010), Amelioration of STZ induced Type I diabetic nephropathy in rats by a phytomedicine: Gmelina arborea presented at Experimental Biology 2010, Anaheim, CA USA. 

• Shah D, Londhe V (April 2010), Formula optimization of levamisole loaded chitosan nanoparticles by 23 factorial design presented at First World Conference on Nanomedicine and Drug Delivery (WCN-2010), Kottayam, Kerala.

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