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RESEARCH (2012-13)

Publications (2012-2013)

• Kumar M, Pandita N, Pal A. LC-MS/MS as a tool for identification of bioactive compounds in marine sponge Spongosorites halichondriodes (Dendy 1905). Toxicon. August 2012, 60(6):1135-1147. 

• Shah R, Sharma N, Patel V, Savai J, Saraswathy N. Validation HPLC fingerprint analysis for Simultaneous Determination of Quercetin and Kaempferol in Methanolic Extract of Tridax procumbens. International Journal of Pharmaceutical and Biological Research. August-September 2012, 3(4):166-174. 

• Waykar R, Kulkarni Y. Development and Bioequivalence study of Olanzapine 10 mg Tablets. International Journal of Pharmaceutical Sciences & Research. September 2012, 3(9):3370-3375. 

• Patel JR, Barve KH. Intestinal Permeability of Lamivudine Using Single Pass Intestinal Perfusion. Indian Journal of Pharmaceutical Sciences. September-October 2012, 74(5):478-481. 

• Rane RA, Sahu NU, Shah CP. Synthesis and antibiofilm activity of marine natural product-based 4-thiazolidinones derivatives. Bioorganic & Medicinal Chemistry Letters. October 2012, 22(23):7131-7134. 

• Babar V, Thomas R, Bhaskar M. Immunomodulatory activity of Lactobacillus sporogenes. International Journal of Therapeutic Applications. October 2012, 3:32-38. 

• Tripurasundari P, Prabhakar B, Sharma M, Chaitanya K. Formulation and Evaluation of Alcohol Resistant Matrix Tablets of Metformin HCl Employing Various Polymers. International Journal of Pharmaceutical Sciences Review and Research. October 2012, 16(2):94-96. 

• Kaur G, Dave U, Vadodaria K. Simultaneous estimation of piperine, quercetin, and curcumin in a Mixture using U.V-visible spectrophotometer and method Validation. International Journal of Therapeutic Applications. October 2012, 8:14-17. 

• Agrawal S, Ghorpade S, Gurjar P. Standardization of polyherbal formulation: Arshonyt Forte. Global Journal of Research on Medicinal Plants & Indigenous Medicine. October 2012, 1(10):516-523. 

• Shelke SH, Mhaske PC, Nandave M, Narkhade S, Walhekar NM, Bobade VD. Synthesis and pharmacological evaluation of a novel series of 3-aryl-2-(2-substituted-4-methylthiazole-5-yl) thiazolidin-4-one as possible anti-inflammatory and antimicrobial agents. Bioorganic & Medicinal Chemistry Letters. October 2012, 20:6373-6376. 

• Joshi C, Savai J, Varghese A, Pandita N. Validated HPTLC Fingerprint Analysis for Simultaneous Estimation of Quercetin, Kaempferol and Asiatic Acid in Leaves of two Different Chemotypes of Centella asiatica. International Journal of Pharmaceutical and Biological Research. October-November 2012, 3(5):202 – 212. 

• Bhatt L, Addepalli V. Attenuation of Cardiac Autonomic Neuropathy and Left Ventricular Function by Inhibition of Matrix Metalloproteinase 2 & 9 in Diabetic Rats. Circulation. November 2012, 126:A18480. 

• Dunkern T, Prabhu A, Kharkar PS, Goebel H, Rolser E, Burckhard-Boer W, Arumugam P, Makhija MT. Virtual and Experimental High-Throughput Screening (HTS) in search of Novel Inosine 5’-monophosphate dehydrogenase II (IMPDH II) Inhibitors. Journal of Computer Aided Molecular Design. November 2012, 26(11):1277-1292. 

• Majumdar P. Emotional Marketing - Chasing the "Share of Heart” of your prospective customers. Asia Pacific Journal of Marketing & Management Review. November 2012, 1(3):68-73. 

• Addepalli V. Targeting overactivation of MMPs in cardiovascular dysfunctions of diabetes. Indian Journal of Hypertension. Hypertension. November 2012, 59. 

• Megha S, Rakesh BP, Vishwanath DP, Mukul Jain, Addepalli V. Renoprotective activity of aliskiren, a rennin inhibitor in cyclosporine induced hypertensive nephropathy in dTG mice. Indian Journal of Hypertension. Hypertension. November 2012, 67. 

• Sharma G, Addepalli V, Chintamaneni M, Majumdar D. Prescription review study of antihypertensive and hypolipidemic drugs in patients with cardiovascular disorders in south Delhi Hospital. Indian Journal of Hypertension. Hypertension. November 2012, 69. 

• Bhonsle N, Barve K, Shah P. Thyroid Hormone & Its Analogues: Prevention of Postmenopausal CVD. Indian Journal of Hypertension. Hypertension. November 2012, 73. 

• Menon SM, Kaur G. Low Dose Naltrexon (LDN) - A potential target for TLR4 expression in hypertension. Indian Journal of Hypertension. November 2012, 79. 

• Kamble P, Selvarajan K, Narasimhulu CA, Nandave M, Parthasarathy S. Aspirin may promote mitochondrial biogenesis via the production of hydrogen peroxide and the induction of Sirtuin 1/PGC-1 agenes. European Journal of Pharmacology. December 2012, 699:55-61.

• Wairkar S, Ambike A, Paradkar AR. Characterization of Cashew Nut Gum as a Binder in Tablet Formulation. International Journal off Pharmaceutical Research. December 2012, 4(4):95-98. 

• Kulkarni YA, Yele VU, Addepalli V, Kulkarni KS. Non-alcoholic fatty liver disease: introspection. Pharmacology Online. December 2012, 3:104-112. 

• Kale PP, Addepalli V. Assessment of antidepressant activity of reboxetine in augmentation with caffeine using despair swim test and tail suspension test. International Journal of Developmental Neuroscience. December 2012, 30(8):640. 

• Waykar R, Kulkarni Y. A pharmacovigilance study of first-line drugs for hypertension. Indian Journal of Hypertension. November 2012, 81. 

• Gaud RS. Role of life sciences for growth of society. Express Pharma. December 2012. 

• Bhaskar M, Lund K, Chintamaneni M. Role of Indigenous Plants in inhibition of Acetylcholinesterase activity. Indian Journal of Pharmacology (Abstract). December 2012, 44:S16. 

• Kale PP, Addepalli V. Reduction in Behavioural paradigms like locomotion, exploration and increased anxiety due to pre-exposure to tail suspension test. Indian Journal of Pharmacology (Abstract). December 2012, 44:S69. 

• Kaur G, Chintamaneni C. Evaluation of Anti-hyperlipidemic Potential of Combinatorial Extract of Curcumin, Piperine and Quercetin in Triton-induced Hyperlipidemia in Rats. Science International. January 2013, 1(3):57-63. 

• Joshi A, Savai J, Varghese A, Pandita N. Validated HPTLC Fingerprint Analysis for Simultaneous estimation of Gallic acid, Ethyl gallate and Tetragalloyl in the bark of two chemotypes of Terminalia arjuna. International Journal of Biological Science and Ayurveda Research. January 2013, 1(2):63-80. 

• Kulkarni YA, Chavan D, Shah K. Toxicity study and analgesic activity of Gmelina arborea extract and its fractions. Journal of Natural Pharmaceuticals. January-June 2013, 4(1):71-74. 

• Chawla P, Kulkarni K, Goyal R, Pamnani C, Nandave M. Comorbid Conditions Warrants Antibiotic Dosage Adjustment in Renal Failure. Indian Journal of Hospital Pharmacy. January 2013, 49:3-6. 

• Jagtap A, Bhaskar M. Evaluation of Antidepressant and Antinociceptive Activity of Escitalopram. Indian Journal of Pharmaceutical Education and Research. January-March 2013, 47(1):97-102. 

• Saraswathy N, Yeole GS, Parikh AJ, Chintamaneni M. Production and Optimization of protease from Bacillus licheniformis NCIM 2044. Asian Journal of Pharmacy and Life Science. January-March 2013, 3(1):9-15. 

• Savai J, Varghese A, Pandita N. Lack of the cytochrome P450 3A interaction of methanolic extract of Withania somnifera, Withaferin A, Withanolide A and Withanoside IV. Journal of Pharmaceutical Negative Results. January-December 2013, 4(1):26-32. 

• Patel D, Kaur G, Sawant M, Deshmukh P. Herbal Medicine: A natural cure to arthritis. Indian Journal of natural products and Resources. March 2013, 4(1):27-35. 

• Nayadu S, Behera D, Sharma M, Kaur G, Gudi G. Fluorescent probe based CYP inhibition assay: a high throughput tool for early drug discovery screening. International Journal of Pharmacy and Pharmaceutical Science. April 2013, 5(2):303-307. 

• Devani U, Pandita N, Kachwala Y. Evaluation of inhibitory activity of Vitex nirgundo and Terminalia chebula by alpha amylase inhibition assay in management of diabetes. Asian Journal of Plant Science and Research. April 2013, 3(2):6-14. 

• Shende PK, Shrawne C, Gaud RS. Multi-layer Tablet: Current scenario and recent advances. International Journal of Drug Delivery. April 2013, 4(4):418-426. 

• Barve K. Herbs in the treatment of diabetes induced erectile dysfunction. Journal of Pharmacy and Phytotherapeutics. April 2013, 1(2):2-8. 

• Barve KH, Ojha N. Effective detoxification of Abrus precatorius Linn. seeds by Shodhana. Journal of Ayurveda and Integrative Medicine. April-June 2013, 4(2):82-85. 

• Londhe VY, Thakkar V, Ranade SC. Topical delivery of Lornoxicam: Design, Evaluation and effect of penetration enhancers. Indo American Journal of Pharmaceutical Research. May 2013, 3(4):3174-3181. 

• Saraswathy N, Patel V, Sharma N, Savai J, Chintamaneni M. Validated HPTLC Method for Simultaneous Determination of Quercitin and Kaempferol in Methanolic Extract of Tridax procumbens. International Journal of Pharmaceutical Research and Development. May 2013, 5(3):114-119. 

• Gopishetty B, Zhang S, Kharkar PS, Antonio T, Reith M, Dutta AK. Modification of agonist binding moiety in hybrid derivative 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-1-ol/-2-amino versions: Impact on functional activity and selectivity for dopamine D2/D3 receptors. Bioorganic & Medicinal Chemistry. May 2013, 3164-3174.

• Thakar DS, Varghese A. Bioanalytical Method Development and Validation of Bupropion Hydrochloride in Rat Plasma by RP-HPLC. International Journal of Pharma Bioscience and Technology. May 2013, 1(1):20-26. 

• Tripurasundari P, Chaithanya KK, Gupta VRM, Prabhakar B, Desai T. Formulation and Evaluation of Alcohol Resistant Dosage Forms of Glipizide. International Journal of Pharmaceutical Sciences and Research. May 2013, 4(5):1998-2001. 

• Swathimutyam P, Prabhakar B. A review on solid lipid nanoparticles. International Journal of Pharmaceutical Sciences Review and Research. May-June 2013, 20(2):196-206. 

• Shende PK, Vellody VV, Gaud RS. Tab-in-tab formulation of ramipril and nifedipine for effective anti-hypertensive activity. Journal of Pharmacy Research. June 2013, 6(6):656-662.

Books (2012-2013)

• Israni D, Goyal RK (2012), Acne Vulgaris associated with Polycystic Ovary Syndrome (PCOS), LAP Lambert Academic Publishing, Germany. 

• Goyal RK, Parikh RK, Patel M (2012), A Text book of Hospital Pharmacy, BS Shah Prakashan, Ahmedabad. 

• Kulkarni Y, Gokhale SB, Kalaskar MG, Yele SU (2012), Pharmacognosy of Animal Drugs, Nirali Prakashan, Pune.

Book Chapters (2012-2013)

• Londhe V, Shah D, Shah R (2012), Chitosan Nanoparticles, In: Nanomedicines and Cancer Therapies, Apple Academic Press, Toronto, New Jersey & CRC Press, Taylor & Francis. 

• Gatne D, Addepalli V, Santani DD (2012), Modulatory role of VEGF in angiogenesis for cell survival, Cardiac adaptations, In: Molecular Mechanisms, Springer publications, USA. 

• Kaur G, Chintamaneni M (2013), Antiobesity and Antidiabetic effects of Combinatorial extract of Curcumin - Integration of traditional and modern concepts, In: Obesity Epidemic, iConcept Press, Australia. 

• Nandave M, Goyal R (2013), Development & Adaptation in Diabetic Cardiomyopathy, In: Adaptation Biology and Medicine, Narosa Publishing House, New Delhi. 

• Gatne D, Addepalli V (2013), Overview of Angiogenesis Inhibitors from Natural Sources, In: Biochemical Basis and Therapeutic Implications of Angiogenesis, Advances in Biochemistry in Health and Disease, Springer Science & Business Media, New York, USA.

Paper Presentations (2012-2013)

• Sherje A, Londhe V (October 2012), Study of inclusion complexes of cyclodextrins & paliperidone: preparation & characterization presented at AAPS 2012 Annual Conference and Exhibition, Chicago, USA. 

• Thakker VP, Londhe V, Ranade S, Desai N (October 2012), Formulation and evaluation of topical gel of lornoxicam, a Non-Steroidal Anti-Inflammatory Drug (NSAID) presented at AAPS 2012 Annual Conference and Exhibition, Chicago, USA. 

• Bhatt L, Addepalli V (November 2012), Attenuation of Cardiac Autonomic Neuropathy and Left Ventricular Function by Inhibition of Matrix Metalloproteinase 2 & 9 in Diabetic Rats presented at American Heart Association (AHA) Conference, Los Angeles, California, USA. 

• Ranade SC, Bajaj AN, Londhe VY, Babul N, Kao D, Singh AH (January 2013), Novel topical film forming polymeric gels of mepivacaine presented at 13th International Symposium of CRS-Indian Chapter on Advances in Technology and Business Potential of New Drug Delivery Systems, Mumbai, Maharashtra. 

• Sangave P, Patel J, Vora M, Tharepel LJP, Nandave M, Kharkar PS (February 2013), Venturing into Novel Chemical Space based on Molecular Formula (MF): Concept and Potential Applications presented at 6th RBF International Symposium Advances in Translational Research and Development, Ahmedabad, Gujarat. 

• Rawat S (February 2013), A study on Cultural Intelligence: The mediating effect of Job Satisfaction and Cross Cultural Adjustment on Expatriates Intention to Stay presented at International HR Conference, Kolkata. 

• Borhade S, Khandare P, Kharkar P (March 2013), Shape and Electrostatic Similarity Analyses of Non-Steroidal Anti-inflammatory Drugs (NSAIDs): Implications for Drug Repurposing presented at 19th ISCB International Conference, Udaipur, Rajasthan. 

• Yadav R, Khandare P, Kharkar PS (March 2013), Azaspirocycles in Small Molecule Drugs: A Molecular Docking Investigation presented at 19th ISCB International Conference, Udaipur, Rajasthan. 

• Gadekar P, Kharkar P, Mehta C, Bose J, Roychowdhury A, Sarveswari S, Sharma R (March 2013), Design, Synthesis and Evaluation of Cyanoguanidine based New Chemical Entities as IGF1R Inhibitors presented at 19th ISCB International Conference, Udaipur, Rajasthan. 

• Raulgaonkar H (March 2013), Ready to Share presented at International Research Conference 2013, Mumbai, Maharashtra. 

• Gandhi P, Gudi G, Jadhav S, Kaur G (March 2013), Inhibition of cyp11a1 and adrenal toxicity in rats: In vitro assay development & validation presented at 5th International Symposium on Drug Metabolism and Pharmacokinetics (DMPK), Chandigarh, Punjab. 

• Varghese A, Savai J, Pandita N, Gaud RS (March 2013), Investigation of CYP3A Inhibition Potential of Methanolic, Hydromethanolic, Aqueous Extract of Terminalia arjuna, Arjunic Acid and Arjungenin in Rat and Human Liver Microsomes presented at 5th International Symposium on Drug Metabolism and Pharmacokinetics (DMPK), Chandigarh, Punjab. 

• Sneha Ranade, Amrita Bajaj, Vaishali Londhe, Babul Najib, Kao D (April 2013), Evaluation of Novel Film Forming Analgesic Formulations for Dermal Application presented at Innovation in 21st Century: Clinical Pharmacology in current and Future environment, Mumbai, Maharashtra. 

• Kharkar PS, Nandave M (June 2013), Molecular Formula (MF) Search as a Novel Strategy for Venturing into Novel Chemical Space: A Detailed Investigation presented at Gordon Research Conference (GRC) on Bioorganic Chemistry, New Hampshire, USA.

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