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RESEARCH (2013-14)

Publications (2013-2014)

• Londhe V, Desai N. Comparative In-Vitro Analysis of Different Available Brands of Ibuprofen Tablets in India using Statistical Parameters. International Journal of Pharmaceutical Sciences Review and Research. July-August 2013, 21(1):205-208. 

• Ojha N, Prabhakar B. Advances in solubility enhancement techniques. International Journal of Pharmaceutical Sciences Review and Research. July-August 2013, 21(2):351-358. 

• Rane S, Prabhakar B. Optimization of Paclitaxel containing pH-sensitive Liposomes by 3 Factor, Level Box-Behnken Design. Indian Journal of Pharmaceutical Sciences. July-August 2013, 75(4):420-426. 

• Wairkar S, Gaud RS. Solid Dispersions: Solubility Enhancement Technique for Poorly Soluble Drugs. International Journal of Research in Pharmaceutical and Biomedical Sciences. July-September 2013, 4(3):847-854. 

• Swathimuthyam P, Prabhakar B. Review on Polymers in drug delivery. American Journal of Pharmtech Research. August 2013, 3(4):900-917. 

• Kulkarni K, Addepalli V. Effects of Gmelina arborea extract on experimentally induced diabetes. Asian Pacific Journal of Tropical Medicine. August 2013, 6(8):602-608. 

• Bhandare R, Canney DJ. Bioisosteric Replacement and Related Analogs in the Design, Synthesis and Evaluation of Ligands for Muscarinic Acetylcholine Receptors. Medicinal Chemistry. September 2013, 9:1-14. 

• Kumar M, Pal AK. GC-MS Analysis of Some Bioactive Constituents from the Marine Sponge Spongosorites halichondriodes (Dendy, 1905). Chemistry of Natural Compounds. September 2013, 49(4):771-772. 

• Ramdhave AS, Patel D, Ramya I, Nandave M, Kharkar P. Targeting Heat Shock Protein 90 for Malaria. Mini- Reviews in Medicinal Chemistry. September 2013, 13:1-18. 

• Kulkarni YA, Panjabi R, Patel V, Tawade A, Gokhale A. Effect of Gmelina arborea Roxb. in experimentally induced inflammation and nociception. Journal of Ayurveda and Integrative Medicine. July-September 2013, 4(3):152-157. 

• Kale PP, Addepalli V, Ghadawale SR. Impact of pre-exposure of tail suspension on behavioural parameters like locomotion, exploration, and anxiety in mice. Indian Journal of Experimental Biology. September 2013, 51:732-738. 

• Nandave M, Ojha SK, Kumari S, Nag TC, Mehra R, Narang R, Arya DS. Cardioprotective effect of root extract of Picrorhiza kurroa (Royle Ex Benth) against isoproterenol-induced cardiotoxicity in rats. Indian Journal of Experimental Biology. September 2013, 51:694-701. 

• Geete SS, Kaur G, Goyal RK, Pamnani C. Emergence of Resistance to Fluoroquinolone Utilized as Second Line Treatment for Tuberculosis. Indian Journal of Hospital Pharmacy. September 2013, 50:122-125. 

• Swathimutyam P, Prabhakar B, Panda DK. Scientific tools for characterization of surface morphology of solid state pharmaceuticals. World Journal of Pharmacy and Pharmaceutical Sciences. October 2013, 2(5):3554-3566. 

• Gurjar PN, Chouksey S, Patil G, Naik N, Agrawal S. Carbon Nanotubes: Pharmaceutical Applications. Asian Journal of Biomedical & Pharmaceutical Sciences. October 2013, 3(23):8-13. 

• Acharya PC, Bansal R. Synthesis and Antiproliferative Activity of Some Androstene Oximes and Their O-Alkylated Derivatives. Archiv der Pharmazie (Arch Pharm (Weinheim). December 2013, 346:1-7. 

• Kaur G. Polypharmacy: The past, present and the future" - Letter To Editor. Journal of Advanced Pharmaceutical Technology & Research. October-December 2013, 4(4): 224-225. 

• Bhaskar M, Chintamaneni M. Ameliorating oxidative stress induced mitochondrial dysfunction. Indian Journal of Pharmacology. December 2013, 45(1):S34. 

• Barve K, Bhonsale N. Diabetic Cardiomyopathy Therapy: One of the Myriad Effects of Guggul. Indian Journal of Pharmacology. December 2013, 45(1):S60. 

• Garud MS, Agarwal S, Kulkarni YA. Anti-Nociceptive and Anti Inflammatory Activity of Celastrus paniculatus. Indian Journal of Pharmacology. December 2013, 45(1):S114. 

• Meghani N, Mankani H, Saraswathy N. Synthesis of Silver Nanoparticles of Aqueous Extract of Plant Lantana camara and Evaluation of its Antimicrobial Activity. World Journal of Pharmaceutical Research. January 2014, 3(1):1339-1351. 

• Bhilegaonkar S, Gaud RS. Preparation of Nanoparticles of Candesartan Cilexetil by Ionotrophic Gelation Technique and their Evaluation. International Journal of Pharmacy. January 2014, 4(1):93-99. 

• Bhilegaonkar S, Gaud RS. Change in Site of Release Offers Advantages for Candesartan Cilexetil. International Journal of Pharmaceutical Sciences Review and Research. January-February 2014, 4:20-23.

• Gaud RS, Londhe V, Agrawal S. Niosomes: Layered Delivery System for Drug Targeting. International Journal of Scientific Research. January 2014, 3(1):413-417. 

• Pandey D, Iyer G. A Study on Impact of financial management on Business Performance. SHODH, Pioneer Journal Institute of IT & Management. January-June 2014, 10(1):17-19. 

• Kharkar PS. Drugs acting on central nervous system (CNS) targets as leads for non-CNS targets. F1000Research. February 2014, 3(40):1-6. 

• Bhaskar M, Chintamaneni M. Withania somnifera and Eclipta alba ameliorate oxidative stress induced mitochondrial dysfunction in an animal model of Alzheimer’s disease. American Journal of Phytomedicine & Clinical Therapeutics. February 2014, 2(1):140-152. 

• Pethe A, Rathi A. Comparative Evaluation of film forming properties of some natural polymers. International Journal of Pharmacy. February 2014, 4(1):347-356. 

• RS Gaud, Tripurasundari P, Shah R. Formulation and Evaluation of Febuxostat Nanoparticles. American Journal of Pharmtech Research. February 2014, 4(1):378-388. 

• Verma V, Sangave P. Review on Non-Viral Delivery Systems for siRNA. International Journal of Pharmaceutical Sciences and Research. February 2014, 5(2):294-301. 

• Kaur G, Daftardar S, Barve KH. Modifying Anti-Inflammatory Effect of Diclofenac with Murraya koenigii. Recent Patents on Inflammation & Allergy Drug Discovery February 2014, 8(1):77-81. 

• Meghani N, Suares D. Self micro-emulsifying drug delivery system (SMEDDS): A promising tool to improve bioavailability. Journal of Pharmacy and Phytotherapeutics. February 2014, 2(1):17-22. 

• Kharkar PS, Warrier S, Gaud RS. Reverse docking: a powerful tool for drug repositioning and drug rescue. Future Medicinal Chemistry. March 2014, 6(3):333-342. 

• Patel ZN, Saraswathy N. Biosurfactant: An Environment Friendly Substitute to Surfactant. World Journal of Pharmaceutical Research. March 2014, 3(2):1968-1977. 

• Saraswat MS, Addepalli V, Jain M, Pawar VD, Patel RB. Renoprotective activity of aliskiren, a renin inhibitor in cyclosporine A induced hypertensive nephropathy in dTG mice. Pharmacological Reports. March 2014, 66:62-67. 

• Kaur G, Somaiya R, Wasim M, Buttar HS. Cardioprotective Effects of Bovine Colostrum Against Isoproterenol-induced Myocardial Infarction in Rats. Journal of Pharmacology and Toxicology. March 2014, 9(1):37-45. 

• Sequeira E, Saraswathy N. Snapshot on Potential involvement of enzyme Secretase in Alzheimer`s disease. World Journal of Pharmacy and Pharmaceutical Sciences. April 2014, 3(3):443-462. 

• Shah K, Borhade S, Londhe V. Utilization of Co-crystallization for solubility enhancement of a poorly soluble antiretroviral drug: Ritonavir. International Journal of Pharmacy and Pharmaceutical Sciences. April 2014, 6(2):556-558. 

• Kumar M, Shah B. Comparative structural morphometry and elemental composition of three marine sponges from Western Coast of India. Microscopy Research and Technique. April 2014, 77(4):296-304. 

• Varghese A, Savai J, Pandita N, Gaud RS. Species Related Differences in In Vitro Metabolism of Phenacetin, A Probe Substrate for CYP1A Enzyme, and Enzyme Kinetic Parameters of Phenacetin. International Journal of Pharma Medicine and Biological Sciences. April 2014, 3(2):21-32. 

• Varghese A, Pandita N, Gaud RS. In vitro and in vivo Evaluation of CYP1A Interaction Potential of Terminalia Arjuna Bark. Indian Journal of Pharmaceutical Sciences. April 2014, 76(2):138-147. 

• Barve K, Chodankar R. Does copper enhance the antihypertensive effect of Elaeocarpus ganitrus in experimentally induced hypertensive rats? Journal of Ayurveda & Integrative Medicine. April-June, 2014, 5(2):76-79. 

• Mehta A, Thaker A, Londhe V, Nandan SR. Reinvestigating Raney nickel mediated selective alkylation of amines with alcohols via hydrogen autotransfer methodology. Applied Catalysis A: General. May 2014, 478:241-251. 

• Daftary AD, Upadhya A. Coupling of two purification methods: Ammonium Sulphate Precipitation and Aqueous Two Phase Systems. International Journal of Engineering Research and Science & Technology. May 2014, 3(2):38-45. 

• Swathimutyam P, Prabhakar B. A Review on Application of Probiotics. The International Journal’s Research Journal of Social Science & Management. May 2014, 4(1):37-45. 

• Nandave M, Chinta PK, Tambe S, Umrani D. Pharmacological Inhibition of NLRP3 Inflammasome by Parthenolide Improves Obesity-Induced Insulin Resistance in Diet-Induced Obese Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. May 2014, 34:A601.

• Londhe V, Bajaj A, Ranade S, Kao D, Babul N. Fabrication of polymeric film forming topical gel. International Journal of Pharmaceutical Sciences Review and Research. May-June 2014, 26(2):306-313. 

• Saraswathy N, Sawant R. Protease: An enzyme with multiple Industrial Applications. World Journal of Pharmacy and Pharmaceutical Sciences. June 2014, 3(6):568-579. 

• Ranade S, Londhe V, Bajaj A. Microemulsion based gels for targeting neuropathic pain. International Journal of Pharmaceutical Sciences and Research. June 2014, 5(6):2515-2524. 

• Bhilegaonkar S, Gaud RS. Preparation of nanoparticles of Candesartan cilexetil by use of supercritical fluid technology and their evaluation. Journal of Pharmacy Research. June 2014, 8(6):779-785. 

• Rane RA, Nandave M, Nayak S, Naik A, Shah D, Sahu NU. Synthesis and pharmacological evaluation of marine bromopyrrole alkaloid-based hybrids with anti-inflammatory activity. Arabian Journal of Chemistry. June 2014. 

• Dunkern T, Chavan S, Bankar D, Patil A, Kulkarni P, Kharkar PS, Prabhu A, Goebel H, Rolser E, Burckhard-Boer W, Arumugam P, Makhija MT. Design, synthesis and biological evaluation of novel inosine 5’-mono-phosphate dehydrogenase (IMPDH) inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. June 2014, 29(3):408-419. 

• Rane RA, Sahu NU, Shah CP, Shah NK. Design, synthesis and antistaphylococcal activity of marine pyrrole alkaloid derivatives. Journal of Enzyme Inhibition Medicinal Chemistry. June 2014, 29(3):401-407.

Book Chapters (2013-2014)

• Barve KH, Pawar AS (2013), Novel approaches to the therapy of depression, In: Recent developments in neurological diseases, Research signpost.

• Kharkar PS (2013), In silico absorption, distribution, metabolism and excretion, In: In silico drug discovery and delivery, Future Science Group. 

• Addepalli V, Gatne D (2014), Restoration of Angiogenesis: A Promising Therapeutic Strategy in Diabetic Cardiomyopathy, In: Diabetic Cardiomyopathy Biochemical and Molecular mechanism, Springer, USA. 

• Bhatt LK, Addepalli V (2014), Targeting Matrix Metalloproteinase 2 and 9 for Treatment of Cardiovascular Dysfunction of Diabetes, In: Diabetic Cardiomyopathy Biochemical and Molecular mechanism, Springer, USA. 

• Daftardar S, Kaur G, Addepalli V (2014), Nutraceutical Approaches in the Management of Cardiovascular Dysfunctions Associated with Diabetes mellitus, In: Diabetic Cardiomyopathy Biochemical and Molecular mechanism, Springer, USA. 

• Nandave M, Ramdhave A, Goyal RK (2014), Liver and Fat in Type 2 Diabetes: New Insights and Clinical Relevance (Vol. 9), In: Diabetic Cardiomyopathy Biochemical and Molecular mechanism, Springer, USA. 

• Kulkarni YA, Warrier S, Makadiya V (2014), Bauhinia variegata (Caesalpiniaceae): A Review of its Traditional Uses, Pharmacognosy, Phytochemistry, Pharmacology and Analysis, In: Bioactive Phytochemicals: Perspectives for Modern Medicine (Vol. 2), Daya Publishing House, New Delhi. 

• Nandave M, Patel D, Chandarana A (2014), Chronopharmacology: Diurnal Variation of Drug Action, In: Advanced Pharmacology, Jaypee Brothers Medical Publishers. 

• Nandave M (2014), Medication Errors, In: Advanced Pharmacology, Jaypee Brothers Medical Publishers. 

• Nandave M (2014), Drug-Drug Interactions, In: Advanced Pharmacology, Jaypee Brothers Medical Publishers. 

• Kumar MS, Mishra S (2014), Pharmacology and Health Benefits of Bioactive Food Sources, In: Functional Foods and Dietary Supplements: Processing Effects and Health Benefits, John Wiley and Sons, Wiley-Blackwell.

Paper Presentations (2013-2014)

• Warrier S, Kharkar PS (September 2013), Adventures in Chemical Space: Utility of Constitutional Isomers in Drug Discovery presented at Recent Advances in Computational Drug Design, Bangalore, Karnataka. 

• Kulkarni Y (October 2013), Attenuation of diabetic nephropathy by natural products presented at International Conference and Exhibition on Pharmacognosy, Phytochemistry & Natural Products, Hyderabad, Andhra Pradesh. 

• Prabhakar B, Desai C (February 2014), Cyclodextrin nanosponges for solubility enhancement and release modulation of cilostazol presented at Nano Scitech 2014, Chandigarh, Punjab. 

• Bhandare R, Gao R, Canney DJ, Kharkar PS (February 2014), Pharmacophoric and Docking Analysis of Five-Substituted 3,3-Diethyl-4,5-Dihydro-2(3h)-Furanones and their Homologs as Muscarinic Receptor Ligands presented at Temple School of Pharmacy Research Recognition Day, Philadelphia, USA. 

• Verma V, Nandave M, Kulkarni YA, Sangana RR, Punde R, Sahu R, Ahmed T (March 2014), In vivo Pharmacokinetic Interaction Study of Sulfasalazine with Pantoprazole in Male SD Rats presented at 6th International Symposium on Drug Metabolism & Pharmacokinetics - DMPK 2014, Mohali, Punjab. 

• Sawant R, Gudi G, Jadhav SB, Addepalli V (February-March, 2014), Dexamethasone-Mediated Induction of CYP3A and P-gp in Rat Intestine and Liver presented at 6th International Symposium on Drug Metabolism & Pharmacokinetics - DMPK 2014, Mohali, Punjab. 

• Nagari T, Gudi G, Kaur G (February-March, 2014), Dexamethasone and Pyridine Mediated CYP450 Enzyme Induction in Rats presented at 6th International Symposium on Drug Metabolism & Pharmacokinetics - DMPK 2014, Mohali, Punjab. 

• Kaur G, Yadav R (April 2014), The Myriad Actions of Bovine Colostrum presented at 7th International Annual Conference Clinical Pharmacology - Translational Research: Patient to Public Health, Mumbai, Maharashtra. 

• Chinta P, Tambe S, Nandave M, Umrani D (May 2014), Pharmacological Inhibition of Nlrp3 Inflammasome by Parthenolide Improves Obesity-Induced Insulin Resistance in Diet-Induced Obese Mice presented at Arteriosclerosis, Thrombosis, and Vascular Biology 2014 Scientific Sessions, Toronto, Ontario, Canada. 

• Shetty S, Thaker A, Gaud R (May 2014), Exploring different membranes for in-vitro evaluation of Gastro-Intestinal Muco-Adhesive Patch System (GIMAPS) of Duloxetine HCl presented at Disso Asia 2014 International Annual Symposium on Dissolution Science, Mumbai, Maharashtra. 

• Suares D, Hiray A (May 2014), Investigation of Various Factors on Ion Exchange Resin Complexation with Fexofenadine Hydrochloride presented at Disso Asia 2014 International Annual Symposium on Dissolution Science, Mumbai, Maharashtra. 

• Bhaskar M, Chintamaneni M (May 2014), Influence of Withania somnifera and Eclipta alba on oxidative stress-induced perturbations in brain monoamines in albino rats presented at 20th International Symposium on Microsomes and Drug Oxidations, Stuttgart, Germany. 

• Jani K, Sangave P (May 2014), Evaluation of pharmacokinetic drug-drug interaction of estradiol with carbamazepine and dexamethasone involving cytochrome P450 induction in female rats presented at 20th International Symposium on Microsomes and Drug Oxidations, Stuttgart, Germany. 

• Mehta C, Sangave P (May 2014), Pharmacokinetic evaluation involving CYP enzymes of oral contraceptives in presence of antiretrovirals in female rats presented at 20th International Symposium on Microsomes and Drug Oxidations, Stuttgart, Germany. 

• Shende P, Kulkarni Y, Gaud RS, Deshmukh K, Cavalli R, Caldera F, Trotta F (May 2014), Acute and Repeated Dose Toxicity Studies on Different Nanosponges presented at 17th International Symposium Cyclodextrin, Saarbrucken, Germany. 

• Bhandare RR, Gao R, Canney DJ, Kharkar P (June 2014), Investigational analysis using pharmacophore and docking studies on five substituted 3,3-diethyl-4,5-dihydro-2(3H)-furanones and their homologs targeted as muscarinic receptor ligands presented at International Conference on Pure and Applied Chemistry 2014, Mauritius. 

• Warrier S, Kharkar P (June 2013), Inverse Virtual Screening in Drug Repositioning: Detailed Investigations and Case Studies presented at International Conference on Pure and Applied Chemistry 2014, Mauritius. 

• Gala V, Kharkar P (June 2014), Solvent-Free Microwave-Assisted Dehydration of Alcohols using LaCl3/H.Al2O3 presented at International Conference on Pure and Applied Chemistry 2014, Mauritius. 

• Acharya P, Kharkar P, Bansal R (June 2014), Hybrids of Steroid and Nitrogen Mustard as Antileukemic Agents: Design, Synthesis, Biological Evaluation and in silico Inverse Screening presented at International Conference on Pure and Applied Chemistry 2014, Mauritius. 

• Kharkar P (June 2014), Mining Chemical Space in Search of Constitutional Isomers: An Innovative Approach to Drug Discovery presented at International Conference on Pure and Applied Chemistry 2014, Mauritius.

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